Polycaprolactone for the Face

  • Pierre Nicolau


The product is a sterile, totally bioresorbable implant, whose principle components are polycaprolactone (PCL) microspheres suspended in a gel carrier of carboxymethyl cellulose. Microspheres have a size range of 25–50 μm, and it should be injected with a 27G needle or a 27G or 25G cannula. It comes in a range of four products, the only difference being the time needed for bulk hydrolysis, 1, 2, 3, or 4 years, allowing for a choice of duration according to the different needs for cosmetic or reconstructive purposes. It may be injected either deep, on the pre-periosteal plane, or superficially, in the hypodermis, as all particulate filler injections should be avoided into the dermis and muscles. The major capacity of collagen stimulation makes it suitable either for volume compensation or for major production of collagen type I, the major component of collagen in normal skin (Nicolau, Plast reconstr Surg 119:2271–2286, 2007).


Polycaprolactyone Dermal fillers Collagen stimulation Skin booster Facial volume 


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© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Pierre Nicolau
    • 1
  1. 1.Pierre Nicolau Clinic of Plastic SurgeryFigueras (Girona)Spain

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