Advertisement

Introduction: What Is Hyaluronic Acid Filler?

  • Nelise Hans
  • Thais Sakuma
Chapter
  • 18 Downloads

Abstract

Hyaluronic acid (HA) is a glycosaminoglycan composed of numerous repetitions of D-glucuronic acid and N-acetyl-D-glucosamine. It is found naturally in many tissues of the human system, including the skin, the synovial fluid of joints, the vitreous humor of eyes, and the cartilage. About 50% of it is found in the skin. In physiological pH, it is a polyanionic polymer and highly loaded, so that it binds extensively to water, being able to retain it up to 1000 times its volume [1] (Fig. 39.1).

References

  1. 1.
    Kablik J, Monheit GD, Yu L, Chang G, Gershkovich J. Comparative physical properties of hyaluronic acid dermal fillers. Dermatol Surg. 2009;35(1):302–12.CrossRefGoogle Scholar
  2. 2.
    Wang F, Garza LA, Kang S, Varani J, Orringer JS, Fisher GJ, Voorhees JJ. In vivo stimulation of de novo collagen production caused by cross-linked hyaluronic acid dermal filler injections in photodamaged human skin. Arch Dermatol. 2007;143(2):155–63.CrossRefGoogle Scholar
  3. 3.
    Glogau RG, Knott HM. Fillers: evolution, regression, and the future. Capitulo 2. Em: soft tissue augmentation. Editado por Jean Carruthers e Alastair Carruthers. Elsevier, 2013.Google Scholar
  4. 4.
    Sundaram H, Cassuto D. Biophysical characteristics of hyaluronic acid soft-tissues fillers and their relevance to aesthetic applications. Plast Reconstr Surg. 2013;132(4Suppl 2):5S–21S.CrossRefGoogle Scholar
  5. 5.
    Pierre S, Liew S, Bernardin A. Basics of dermal filler rheology. Dermatol Surg. 2015;41(Suppl 1):S120–6.CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Nelise Hans
    • 1
  • Thais Sakuma
    • 1
  1. 1.Private practiceCampo GrandeBrazil

Personalised recommendations