Tip Chapter: Low-Level Light Therapy and High-Energy Lasers in Trichology

  • R. Minotto
  • L. Damiani


The mechanism of light therapy is called phototherapy [3, 4]. It requires absorption of a specific wavelength by a light-absorbing molecule (chromophore), which can be produced and synthesized endogenously or applied exogenously to the receptor in cell tissues [3, 9, 12]. Irradiation in the photoreceptor generates a cascade of responses from the cells that leads to modulation of the cell function, proliferation, and repair of damaged cells [3, 9, 12]. The term that describes this “potentiation/cell function modulation” process is called photobiomodulation [3, 4, 9, 12] (Figs.109.1, 109.2, 109.3, and 109.4).


  1. 1.
    Rangwala S, Rashid RM. Alopecia: a review of laser and light therapies. Dermatol Online J. 2012;18(2):3.PubMedGoogle Scholar
  2. 2.
    Avci P, Gupta GK, Clark J, Wikonkal N, Hamblin MR. Low-level laser (light) therapy (LLLT) for treatment of hair loss. Lasers Surg Med. 2014;46(2):144–51.CrossRefGoogle Scholar
  3. 3.
    Jimenez JJ, Wikramanayake TC, Bergfeld W, Hordinsky M, Hickman JG, Hamblim MR, Schachner LA. Efficacy and safety of low-level laser device in the treatment of male and female pattern hair loss: a multicenter, randomized, sham device-controlled, double-blind study. Am J Clin Dermatol. 2014;15(2):115–27.CrossRefGoogle Scholar
  4. 4.
    Kim WS, Lee HI, Lee JW, Lim YY, Lee SJ, Kim BJ, Kim MN, Song KY, Park WS. Fractional photothermolysis laser treatment of male pattern hair loss. Dermatol Surg. 2011;37(1):41–51.CrossRefGoogle Scholar
  5. 5.
    Zarei M, Wikramanayake TC, Falto-Aizpurua L, Schachner LA, Jimenez JJ. Low level laser therapy and hair regrowth: an evidence-based review. Lasers Med Sci. 2015;31:363–71.CrossRefGoogle Scholar
  6. 6.
    Radmanesh M. Paradoxical hypertrichosis and terminal hair change after intense pulsed light hair removal therapy. J Dermatolog Treat. 2009;20:52–4.CrossRefGoogle Scholar
  7. 7.
    Barolet D. Light-emitting diodes (LED) in dermatology. Semin Cutan Med Surg. 2008;27:227–38.CrossRefGoogle Scholar
  8. 8.
    Avram MR, Leonard RT Jr, Epstein ES, et al. The current role of laser/light sources in the treatment of male and female pattern hair loss. J Cosmet Laser Ther. 2007;9:27–8.CrossRefGoogle Scholar
  9. 9.
    Ghanaat M. Types of hair loss and treatment options, including the novel low-level light therapy and its proposed mechanism. South Med J. 2010;103:917–21.CrossRefGoogle Scholar
  10. 10.
    Gupta AK, Daigle D. The use of low-level light therapy in the treatment of androgenetic alopecia and female pattern hair loss. J Dermatolog Treat. 2014;25(2):162–3.CrossRefGoogle Scholar
  11. 11.
    Waiz M, Saleh AZ, Hayani R, Jubory SO. Use of the pulsed infrared diode laser (904 nm) in the treatment of alopecia areata. J Cosmet Laser Ther. 2006;8:27–30.CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • R. Minotto
    • 1
  • L. Damiani
    • 1
  1. 1.Dermatology DepartmentUFCSPA, Hospital Santa Casa de Porto AlegrePorto AlegreBrazil

Personalised recommendations