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Medical Applications of X-Ray Nanochemistry

  • Ting Guo
Chapter
Part of the Nanostructure Science and Technology book series (NST)

Abstract

Three main aspects of medical applications of X-ray nanochemistry are discussed in this chapter. The first part is enhanced X-ray imaging of tumors in animals or phantoms using X-ray absorbing nanomaterials. The second is nanomaterial-assisted cancer treatment using X-rays. The treatment is performed on both cancer cell lines and tumors in animals, which are reviewed in two sections. Theoretical modeling of treatment is also discussed in another section. In addition, pre-clinical and clinical studies and miscellaneous methods such as scanning focusing needle beam X-rays are also presented in this part. The third part is X-ray activated or triggered nanodrug release using X-ray nanochemistry. These nanodrugs resemble prodrugs with the exception of the nanodrugs are activated by X-rays. In addition to these three parts, a general description of in vitro and in vivo protocols is also given at the beginning of the chapter, and recent reviews in these fields are mentioned at the end of this chapter.

Keywords

Biological assays Clinical trials Contrast agents Damage to cells Damage to tumors Delivery of nanomaterials Detection of nanomaterials Endpoints Imaging Imaging of nanomaterials Preclinical trials Simulation of enhancement Targeting Targeting by nanomaterials X-ray-triggered release 

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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Ting Guo
    • 1
  1. 1.Department of ChemistryUniversity of CaliforniaDavisUSA

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