Treponema pallidum Hemagglutination (TPHA) Test
Syphilis is a sexually transmitted disease caused by bacteria called Treponema pallidum, and range from asymptomatic to severe. Patients with suspected syphilis should undergo a non-treponemal screening test (rapid plasma reagin) and positive results must be confirmed with a test specific to T. pallidum antigen. Here, the treponemal test, T. pallidum hemagglutination test, principle, reagents required, steps, and results interpretation in addition to examples to clarify the results interpretation process are described.
KeywordsSyphilis Treponema pallidum Treponemal test TPHA Hemagglutination
- 6.BIOLABO. Haemagglutination assay for qualitative and semi-quantitative determination of antibodies to Treponema pallidum in human serum or plasma. BIOLABO. 2014. Accessed 2 September 2017. Available from: http://www.biolabo.fr/biolabo/pdfs/noticesE/syphilisE/AT-45-00-100-TPHA.
- 7.Human Diagnostics Worldwide. Syphilis TPHA liquid. Human-de. 2014. Accessed 2 September 2017. Available from: http://www.human-de.com/data/gb/vr/lx-tpha.pdf.