Antibody and Antigen Interaction
Most immune assays depend on the interaction between antigens and their specific antibodies. Because of the specificity of the reaction, the interaction between antigens and antibodies is highly utilized to identify either the antigens or the antibodies of interest. In this chapter, the characteristics of antigens, antibodies, and their interactions are described. Moreover, a description of the different and most commonly used dilution methods for serological testing, in addition to general safety rules for working in clinical laboratories, are explored.
KeywordsAntigen Immunogen Antibody Serotyping Precipitation Agglutination Affinity Avidity Dilution Safety
- 3.Coico R, Sunshine G. Immunology: a short course. 7th ed. Chichester, West Sussex; Hoboken, NJ: John Wiley & Sons Inc.; 2015. p. 133.Google Scholar