Assembly of Nuclear Pore Complex

  • Jingjie Yu
  • Joseph Kelich
  • Weidong YangEmail author
Part of the Nucleic Acids and Molecular Biology book series (NUCLEIC, volume 33)


Nuclear pore complexes (NPCs) are multiprotein supercomplexes that serve as gates for nuclear–cytoplasmic transport in eukaryotic cells. The assembly of NPCs is critical for proper cell division and for maintaining normal physiological function of cells. However, the sequential order of NPC assembly is still unclear and controversial results have been obtained from various studies. This review summarizes current understanding on NPC assembly focusing on known protein–protein interactions and regulation pathways.


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© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of BiologyTemple UniversityPhiladelphiaUSA

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