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Warm Autoantibodies During Pregnancy

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Transfusion Management of the Obstetrical Patient
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Abstract

Warm autoantibodies (WAAs) are typically immunoglobulin G (IgG) antibodies directed against red blood cells (RBCs) that react maximally at 37 °C. They are detected in 1:1000 to 1:50,000 of pregnancies. WAAs may rarely cause a warm autoimmune hemolytic anemia (WAIHA), but most WAAs do not result in hemolysis. If WAAs are detected in a pregnant patient, the patient should be evaluated for RBC hemolysis. If there is hemolysis, the patient should be referred to a hematologist for further care. If there is no hemolysis, the patient may be managed similar to a pregnant patient that does not have red cell antibodies.

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Correspondence to Chakri Gavva M.D. .

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Gavva, C. (2018). Warm Autoantibodies During Pregnancy. In: Nester, T. (eds) Transfusion Management of the Obstetrical Patient. Springer, Cham. https://doi.org/10.1007/978-3-319-77140-3_22

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  • DOI: https://doi.org/10.1007/978-3-319-77140-3_22

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-77139-7

  • Online ISBN: 978-3-319-77140-3

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