Testing Algorithm for Rh Immune Globulin Dosing in the Post-natal RhD-Negative Mother
Transfusion medicine physicians have advocated for testing all RhD negative newly delivered mothers with RhD positive babies for the presence of fetal maternal hemorrhage since 1980. Despite this fact, guidelines written for obstetrical groups have not been entirely aligned with the testing algorithm put forth by transfusion medicine groups. This discrepancy led to policies within individual institutions that leave out certain patient groups from the screening protocols, which in turn places the patient at risk for sensitization to D. The literature and controversy surrounding this topic is quite dated; a 2017 update finally aligns the testing recommendations.
KeywordsRh immune globulin RhD negative pregnant patient Rosette test Kleihauer-Betke test
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