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Histology

  • Stefan Dirnhofer
Chapter
Part of the Hematologic Malignancies book series (HEMATOLOGIC)

Abstract

Bone marrow (BM)-based diagnosis of hematologic disorders, in particular lymphoid and myeloid neoplasms, is complex and requires a multidisciplinary, multivalued, and integrative approach that includes morphologic (cytologic and histologic), cytogenetic, and molecular genetic findings and immunophenotyping (flow cytometry and immunohistochemistry). The morphological assessment is based on both the cytology of a bone marrow smear and the histology of a bone marrow trephine biopsy which complement each other.

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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.PathologyUniversity Hospital BaselBaselSwitzerland

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