Metastatic Spine Disease: Critical Evaluation of the Current Literature

  • Adedayo O. Ashana
  • Andrew B. Kay
  • Justin Earl Bird


The treatment of metastatic disease to the spine has evolved substantially over time. Steroids and radiation therapy were initially seen as the primary treatment modalities, as surgery was viewed as ineffective. Surgical treatment became more common after the 2005 Patchell study, and several treatment algorithms were instituted based on its finding. However recent advances in nonsurgical modalities have made nonoperative care the treatment of choice for many patients with metastatic spine disease. In this chapter, critical review of the literature is performed, and available treatment options are summarized.


Spine Metastases Literature review Steroids Radiotherapy Chemotherapy Stereotactic radiosurgery 


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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Adedayo O. Ashana
    • 1
  • Andrew B. Kay
    • 2
  • Justin Earl Bird
    • 3
  1. 1.Department of Orthopedic Spine SurgeryOSS HealthYorkUSA
  2. 2.Department of Orthopaedic SurgeryHouston Methodist HospitalHoustonUSA
  3. 3.Department of Orthopaedic OncologyThe University of Texas MD Anderson Cancer CenterHoustonUSA

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