Early Detection and Screening of Cancer

Chapter

Abstract

Cancer is one of the leading causes of morbidity and mortality worldwide, with approximately 14 million new cases in 2012 (Ferlay et al. Lyon, France: IARC, 2013). It refers to a large group of diseases resulting from abnormal and uncontrolled cell growth and proliferation. Such cells can have the potential to invade or spread to other parts of the body. Malignancy, carcinoma, tumours and neoplasms are other terminologies implying various aspects of this medical condition. In health care strategies and medical practice, screening programmes in both healthy and high-risk populations offer the opportunity to detect cancer early and timely, at a stage before onset of symptoms, and ideally before metastasis. Early detection of cancer can decrease morbidity, improve survival and in some situations treatment may limit to surgical removal alone if identifıed early enough. Mammography in women aged 50–70 years (even possibly starting at 40 years of age) and colonoscopy in the healthy population over 50 years of age play an important role in the early detection of cancer and are included in the recommended guidelines for cancer screening. Cancer is the second leading cause of death in the world can be tackled to an extent by early identification, timely intervention and treatment. Further research is very much needed in quest of easy accessible and acceptable screening methods and novel biomarkers.

References

  1. 1.
    Ferlay J, Soerjomataram I, Ervik M, Dikshit R, Eser S, Mathers C, et al. Cancer incidence and mortality worldwide. Lyon, France: IARC, International Agency for Research on Cancer; 2013.Google Scholar
  2. 2.
    National Cancer Institute. Surveillance research program. http://surveillance.cancer.gov/devcan/.
  3. 3.
    American Cancer Society. The history of cancer. https://www.cancer.org/cancer/cancer-basics/history-of-cancer.html.
  4. 4.
    Sudhakar A. History of cancer, ancient and modern treatment methods. J Cancer Sci Ther. 2009;1(2):1–4.CrossRefPubMedPubMedCentralGoogle Scholar
  5. 5.
    World Cancer Research Fund and American Institute for Cancer Research. Continuous update project. http://www.wcrf.org/int/research-we-fund/continuous-update-project-cup.
  6. 6.
    Kohler LN, Garcia DO, Harris RB, Oren E, Roe DJ, Jacobs ET. Adherence to diet and physical activity cancer prevention guidelines and cancer outcomes: a systematic review. Cancer Epidemiol Biomarkers Prev. 2016;25:1018–28.CrossRefPubMedPubMedCentralGoogle Scholar
  7. 7.
    Kushi LH, Doyle C, McCullough M, et al. American Cancer Society Guidelines on Nutrition and Physical Activity for cancer prevention: reducing the risk of cancer with healthy food choices and physical activity. CA Cancer J Clin. 2012;62(1):30–67.CrossRefPubMedGoogle Scholar
  8. 8.
    GBD 2015 Risk Factors Collaborators. Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet. 2016;388(10053):1659–724.CrossRefGoogle Scholar
  9. 9.
    Nordling C. A new theory on cancer-inducing mechanism. Br J Cancer. 1953;7(1):68–72.CrossRefPubMedPubMedCentralGoogle Scholar
  10. 10.
    Marte B, Eccleston A, Nath D. Molecular cancer diagnostics. Nature. 2008;452(7187):547.CrossRefPubMedGoogle Scholar
  11. 11.
    Knudson A. Mutation and cancer: statistical study of retinoblastoma. Proc Natl Acad Sci U S A. 1971;68(4):820–3.CrossRefPubMedPubMedCentralGoogle Scholar
  12. 12.
    Futreal PA, Coin L, Marshall M, Down T, Hubbard T, Wooster R, Stratton MR. A census of human cancer genes. Nat Rev Cancer. 2004;4(3):177–83.CrossRefPubMedPubMedCentralGoogle Scholar
  13. 13.
    Plummer M, de Martel C, Vignat J, Ferlay J, Bray F, Franceschi S. Global burden of cancers attributable to infections in 2012: a synthetic analysis. Lancet Glob Health. 2016;4(9):e609–16.CrossRefPubMedGoogle Scholar
  14. 14.
    Stewart BW, Wild CP, editors. World cancer report. Lyon, France: International Agency for Research on Cancer; 2014.Google Scholar
  15. 15.
    White JD, Lin H, Jia L, Wu RS, Lam S, Li J, Dou J, Kumar N, Lin L, Lao L. Proceedings of the strategy meeting for the development of an International Consortium for Chinese Medicine and Cancer. J Glob Oncol. 2017;3(6):814–22.CrossRefPubMedGoogle Scholar
  16. 16.
    Oeffinger KC, Fontham ET, Etzioni R, Herzig A, Michaelson JS, Shih YC, et al. American Cancer Society. Breast cancer screening for women at average risk: 2015 guideline update from the American Cancer Society. JAMA. 2015;314(15):1599–614.CrossRefPubMedPubMedCentralGoogle Scholar
  17. 17.
    Saslow D, Solomon D, Lawson HW, Killackey M, Kulasingam SL, Cain J, et al. American Cancer Society; American Society for Colposcopy and Cervical Pathology; American Society for Clinical Pathology. American Cancer Society, American Society for Colposcopy and Cervical Pathology, and American Society for Clinical Pathology screening guidelines for the prevention and early detection of cervical cancer. Am J Clin Pathol. 2012;137(4):516–42.CrossRefPubMedGoogle Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of Food Science and NutritionCollege of Agricultural and Marine Sciences, Sultan Qaboos UniversityMuscatOman
  2. 2.Department of GastroenterologyStarcare Hospital LLCMuscatOman

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