Non-melanoma Skin Cancer with Anemia

  • Rebecca S. ThornhillEmail author
  • Tyler Scott


A 75-year-old man with a history of multiple cutaneous squamous cell carcinomas (SCCs) and chronic lymphocytic leukemia (CLL) presented with a rapidly growing nonscaly nodule adjacent to a site of previous Mohs surgery. Microscopic examination yielded these findings. The correct diagnosis is:
  1. (a)


  2. (b)

    Perineural lymphocytic infiltrates associated with a previous history of SCC

  3. (c)

    Cutaneous lupus erythematosus

  4. (d)

    Small lymphocytic lymphoma/chronic lymphocytic leukemia associated with site of previous surgery and scarring



Small lymphocytic lymphoma Chronic lymphocytic leukemia Lymphocytoma cutis 


  1. 1.
    Diehl LF, Karnell LH, Menck HR. The National Cancer Data Base Report on age, gender, treatment, and outcomes of patients with chronic lymphocytic leukemia. Cancer. 1999;86:2684–92.CrossRefPubMedGoogle Scholar
  2. 2.
    Constanin A, Dasanu M, Alexandrescu D. Risk for second nonlymphoid neoplasms in chronic lymphocytic leukemia. MedGenMed. 2007;9:35–40.Google Scholar
  3. 3.
    Burke JS, Hoppe RT, Cibull ML, Dorfman RF. Cutaneous malignant lymphomas: a pathologic study of 50 cases with clinical analysis of 37. Cancer. 1981;47:300–10.CrossRefPubMedGoogle Scholar
  4. 4.
    Dargent J-L, Henne S, Pranger D, Balzarini P, Sartenaer D, Bulliard G, Rack K, et al. Tumor-forming plasmacytoid dendritic cells associated with myeloid neoplasms. Report of a peculiar case with histopathologic features masquerading as lupus erythematosus. J Cutan Pathol. 2015;43:280–6.CrossRefPubMedGoogle Scholar

Copyright information

© Springer Science+Business Media LLC 2018

Authors and Affiliations

  1. 1.Greenville Health SystemUniversity of South CarolinaGreenvilleUSA
  2. 2.Louisiana State University School of MedicineNew OrleansUSA

Personalised recommendations