The outcome of Mohs micrographic surgery relies heavily on the abilities of the histotechnician. The duties of the Mohs histotechnician require more precision than those of the general histotechnician. Central to this are the understanding and skill set required in preparing sections so the surgeon can assess the entire peripheral margin. Mohs histotechnology training can take place at standard histotechnology education programs or can be learned on the job. It is the experience of the authors that most people who have been trained to cut routine histopathology can be trained to cut Mohs sections.