Vascular Endothelial Growth Factor: The Cornerstone of Vascular Development Factors

  • Andreas Bikfalvi
Chapter

Abstract

In 1986, Napoleone Ferrara and Jean Plouet (Fig. 7.1), both postdoctoral fellows in Denis Gospodarowicz’s laboratory in San Francisco, detected a stimulating activity of endothelial cells in the culture medium of bovine and mouse pituitary cells that was eluted from a heparin-sepharose column at much lower ionic strength than fibroblast growth factors [122, 123].

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Copyright information

© Springer International Publishing AG, part of Springer Nature 2017

Authors and Affiliations

  • Andreas Bikfalvi
    • 1
  1. 1.Angiogenesis and Tumor Microenvironment LaboratoryUniversity of Bordeaux and National Institute of Health and Medical ResearchPessacFrance

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