Anatomic Abnormalities and Recurrent Implantation Failure

  • Jeffrey M. Goldberg
  • Julian Gingold
  • Natalia Llarena
Chapter

Abstract

Intrauterine abnormalities such as myomas, polyps, adhesions, and congenital septa have been shown to adversely affect embryo implantation and pregnancy outcomes. Treating these conditions improves pregnancy rates and outcomes. Hydrosalpinges reduce IVF pregnancy rates by ~50% by impeding embryo implantation. Treating them prior to IVF by salpingectomy, salpingostomy, or tubal ligation restores the success rates back to normal. This chapter reviews the pathophysiology of these abnormalities, therapeutic options, and treatment results.

Keywords

Fibroids Myomas Myomectomy Endometrial polyps Polypectomy Intrauterine adhesions Uterine anomalies Uterine septoplasty Hydrosalpinx Embryo implantation 

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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Jeffrey M. Goldberg
    • 1
  • Julian Gingold
    • 1
  • Natalia Llarena
    • 1
  1. 1.Department of Gynecology and ObstetricsCleveland ClinicClevelandUSA

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