Acute Kidney Injury

  • Ian J. Stewart
  • Joseph J. DuBose


Acute kidney injury (AKI) is clinically diagnosed by evaluating relative changes in serum creatinine or decreases in urine output. AKI is common in critically ill surgical patients and can be a result of hypoperfusion, sepsis, rhabdomyolysis, abdominal compartment syndrome, or contrast-induced nephropathy. In addition to increasing the risk of multi-organ failure and in-hospital death, an episode of AKI is associated with poor long-term outcomes to include mortality, chronic kidney disease, and hypertension. While treatment of AKI is primarily supportive, renal replacement therapy can be initiated in severe cases.


Acute kidney injury Intensive care unit Rhabdomyolysis Abdominal compartment syndrome Renal replacement therapy 


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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Ian J. Stewart
    • 1
  • Joseph J. DuBose
    • 2
  1. 1.Combat Casualty Care Research, Clinical Investigation Facility, David Grant USAF Medical CenterTravis AFBUSA
  2. 2.Division of Vascular SurgeryDavid Grant Medical CenterTravis AFBUSA

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