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Percutaneous Coronary Intervention for Left Ventricular Systolic Dysfunction

  • Sophie Zhaotao Gu
  • Amr Gamal
  • Christopher Eggett
  • Hani Ali
  • Azfar Zaman
  • Richard Edwards
  • Vijay Kunadian
Chapter

Abstract

Heart failure (HF) is a clinical syndrome with symptoms and signs caused by cardiac dysfunction. Its prevalence is estimated at 1–2% in the developed world with an incidence approaching 5–10 per 1000 persons per year. Ischemic heart disease (IHD) is the most common cause of heart failure in the developed world. Heart failure due to ischaemia is associated with worse mortality compared with a non-ischaemic cause. The term ischaemic cardiomyopathy (ICM) has been commonly used to describe impaired left ventricular systolic dysfunction (LVSD: ejection fraction ≤35–40%) resulting from coronary artery disease (CAD). This chapter focuses on the diagnosis and management of ischemic cardiomyopathy. We explore the current evidence base to aid clinical decision-making for invasive versus conservative management. Conventional pharmacological therapy for heart failure will not be discussed in detail in this chapter.

Keywords

Heart failure Ischemic cardiomyopathy Hibernating/viable myocardium Viability testing Revascularization Percutaneous coronary intervention Coronary artery bypass graft Optimal medical therapy Takotsubo cardiomyopathy 

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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Sophie Zhaotao Gu
    • 1
    • 2
  • Amr Gamal
    • 3
  • Christopher Eggett
    • 3
  • Hani Ali
    • 1
    • 2
  • Azfar Zaman
    • 1
    • 2
  • Richard Edwards
    • 3
  • Vijay Kunadian
    • 1
    • 2
  1. 1.Institute of Cellular MedicineNewcastle UniversityNewcastle upon TyneUK
  2. 2.Cardiothoracic Centre, Freeman HospitalNewcastle upon Tyne NHS Foundation TrustNewcastle upon TyneUK
  3. 3.Cardiothoracic Centre, Freeman HospitalNewcastle upon Tyne NHS Foundation TrustNewcastle upon TyneUK

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