IR Playbook pp 451-461 | Cite as

Biopsy Techniques

  • Solomon Abay
  • Adam B. WinickEmail author


Improvements in imaging equipment have allowed for marked advances in biopsy-related minimally invasive procedures. Accuracy and success rates have improved dramatically. Additionally, improvements in device development have allowed for better yield of tissue during biopsy procedures. With the advent of genomics and targeted therapies for cancer, the need for accurate biopsy of suspected cancer lesions will continue to grow in the near future.


Image-guided biopsy 


  1. 1.
    Kaadan AN. Albucasis and thyroid surgery. Paper presented at: 39th international congress on the history of medicine, 2004; Bari, Metaponto Italy.Google Scholar
  2. 2.
    Diamantis A, Magiorkinis E, Koutselini H. Fine-needle aspiration (FNA) biopsy: historical aspects. Folia Histochem Cytobiol. 2009;47(2):191–7.CrossRefPubMedGoogle Scholar
  3. 3.
    Webb AJ. Early microscopy: history of fine needle aspiration (FNA) with particular reference to goiters. Cytopathology. 2001;12:1–6.CrossRefPubMedGoogle Scholar
  4. 4.
    Rosa M. Fine-needle aspiration biopsy: a historical overview. Diagn Cytopathol. 2008;36(11):773–5.CrossRefPubMedGoogle Scholar
  5. 5.
    Farrell RJ, Smiddy PF, Pilkington RM, Tobin AA, Mooney EE, Temperley IJ, et al. Guided versus blind liver biopsy for chronic hepatitis C: clinical benefits and costs. J Hepatol. 1999;30(4):580–7.CrossRefPubMedGoogle Scholar
  6. 6.
    Maya ID, Maddela P, Barker J, Allon M. Percutaneous renal biopsy: comparison of blind and real-time ultrasound-guided technique. Semin Dial. 2007;20(4):355–8.CrossRefPubMedGoogle Scholar
  7. 7.
    Cesur M, Corapcioglu D, Bulut S, Gursoy A, Ender Yilmaz A, Erdogan N, Kamel N. Thyroid. 2006;16(6):555–61. Scholar
  8. 8.
    Watkinson A, Adam A. Interventional radiology: a practical guide, vol. 42. New York: Radcliffe Medical Press; 1996. (ISBN 1 85775031 4)Google Scholar
  9. 9.
    Gervais DA, Sabharwal T, editors. Interventional radiology procedures in biopsy and drainage. London: Springer-Verlag London Limited; 2001. (ISBN 978-1-84800-899-1)Google Scholar
  10. 10.
    Tyng CJ, Almeida MFA, Barbosa PN, Bitencourt AG, Berg JA, Maciel MS, et al. Computed tomography-guided percutaneous core needle biopsy in pancreatic tumor diagnosis. World J Gastroenterol. 2015;21(12):3579–86.CrossRefPubMedPubMedCentralGoogle Scholar
  11. 11.
    Rotten D, Levaillant JM, Leridon H, Letessier A, Sandres M. Ultrasonographically guided fine needle aspiration cytology and core-needle biopsy in the diagnosis of breast tumors. Eur J Obstet Gynecol Reprod Biol. 1993;49:175–86.CrossRefPubMedGoogle Scholar
  12. 12.
    Willems SM, van Deurzen CH, van Diest PJ. Diagnosis of breast lesions: fine-needle aspiration cytology or core needle biopsy? A review. J Clin Pathol. 2012;65:287–92.CrossRefPubMedGoogle Scholar
  13. 13.
    Choi SH, Han KH, Yoon JH, Moon HJ, Son EJ, Youk JH, et al. Factors affecting inadequate sampling of ultrasound-guided fine-needle aspiration biopsy of thyroid nodules. Clin Endocrinol. 2011;74(6):776–82.CrossRefGoogle Scholar
  14. 14.
    Polyzos SA, Anastasilakis AD. Clinical complications following thyroid fine-needle biopsy: a systematic review. Clin Endocrinol. 2009;71:157–65.CrossRefGoogle Scholar
  15. 15.
    Khankan AA, Al-Muaikeel M. Image-guided percutaneous transthoracic biopsy in lung cancer--emphasis on CT-guided technique. J Infect Public Health. 2012;5(Suppl 1):S22–30.CrossRefPubMedGoogle Scholar
  16. 16.
    Otto S, Mensel B, Friedrich N, Schäfer S, Mahlke C, von Bernstorff W, et al. Predictors of technical success and rate of complications of image-guided percutaneous transthoracic lung needle biopsy of pulmonary tumors. PLoS One. 2015;10(4):e0124947.CrossRefPubMedPubMedCentralGoogle Scholar
  17. 17.
    Fryer E, Wang LM, Verrill C, Fleming K. How often do our liver core biopsies reach current definitions of adequacy? J Clin Pathol. 2013–201440;66:1087–9.CrossRefPubMedGoogle Scholar
  18. 18.
    Haugen BR, Alexander EK, et al. American Thyroid Association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer. Thyroid. 2015;26(1):1–133. 2016. Scholar
  19. 19.
    Mueller M, Wittich G, Oeztuerk S, Kratzer W, Haenle M, Mason R. Sonographically guided lymph node biopsy: complication rates. Open J Clin Diagn. 2012;2:30–5.CrossRefGoogle Scholar
  20. 20.
    Zamboni GA, D'Onofrio M, Idili A, Malagò R, Iozzia R, Manfrin E, Mucelli RP. Ultrasound-guided percutaneous fine-needle aspiration of 545 focal pancreatic lesions. AJR Am J Roentgenol. 2009;193(6):1691–5.CrossRefPubMedGoogle Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.University of Virginia Health System, Department of Radiology and Medical ImagingCharlottesvilleUSA

Personalised recommendations