Review of Hemophilia A and B and Perioperative Management in Dentistry
Hemophilia A (classic hemophilia) and hemophilia B (Christmas disease) are inherited disorders of coagulation that can produce life-threatening bleeding. Patients with hemophilia will require special management strategies in order to safely undergo dental treatment. Patient management is optimized when the dental professional has a basic understanding of how these diseases affect hemostasis, is familiar with medical/systemic treatment strategies available to the hematologist, and knows the principles of dental/local management of patients with bleeding risks. In order to help with these goals, this chapter reviews the pathophysiology, clinical presentation, patient evaluation, and basics of medical management of hemophilia. These reviews are presented with an emphasis given to the dental management of patients with hemophilia A and B.
KeywordsHemophilia Hemophilia A Classic hemophilia Hemophilia B Christmas disease Inherited bleeding disorder Desmopressin Fresh frozen plasma Cryoprecipitate Coagulation factors Factors VIII Factor IX Epsilon-aminocaproic acid Tranexamic acid Tranfusion
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