Spitz/Reed nevus is a benign melanocytic neoplasm typically occurring in childhood and adolescence. The diagnosis is based on clinical-dermatoscopic correlation and histopathology. In particular, six main dermatoscopic patterns can be ascribed to Spitz/Reed nevus, namely vascular, globular, starburst, reticular, atypical, and homogenous. Histopathological features of Spitz/Reed nevi show plaque-shaped, well-circumscribed lesions, typically composed of sharply demarcated melanocytic nests within a hyperplastic epidermis.
Ferrara G, Gianotti R, Cavicchini S et al (2013) Spitz nevus, Spitz tumor, and spitzoid melanoma. A comprehensive clinicopathologic overview. Dermatol Clin 31:589–598CrossRefPubMedGoogle Scholar
Ferrara G, Crisman G, Soyer HP et al (2006) Intraepidermal dendritic melanocytes in spitzoid neoplasms. Am J Dermatopathol 28:449–450CrossRefPubMedGoogle Scholar
Argenziano G, Soyer HP, Ferrara G et al (2001) Superficial black network: an additional dermoscopic clue for the diagnosis of spinal and/or epithelioid cell nevus. Dermatology 203:333–335CrossRefPubMedGoogle Scholar