Macular Pigmentation of Uncertain Etiology

  • Johannes F. Dayrit
  • Prasad Kumarasinghe
Part of the Updates in Clinical Dermatology book series (UCD)


Acquired macular pigmentation of uncertain etiology(AMPUE) has certain characteristic hyperpigmentation patterns; they include ashy dermatosis(AD), erythema dyschromicum perstans (EDP), lichen planus pigmentosus (LPP), and idiopathic eruptive macular pigmentation(IEMP). The clinical and histopathological features overlap, and presently there is no consensus on effective treatment. Riehl’s melanosis and IEMP with papillomatosis are two other distinctive pigmentary disorders for which the exact aetiology is not known. All other cases, where the pattern of pigmentation is not characteristic, are best kept under the umbrella of AMPUE until more disease-defining features develop or the etiology becomes clearer. There is a pressing need to fully understand and properly define these skin conditions as patchy hyperpigmentation creates both cosmetic and psychological problems for the darker-skinned populations.


Hyperpigmentation Ashy dermatosis Lichen planus pigmentosus Acquired macular pigmentation Riehl’s melanosis Erythema dyschromicum perstans Idiopathic eruptive macular pigmentation 


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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Johannes F. Dayrit
    • 1
    • 2
  • Prasad Kumarasinghe
    • 3
  1. 1.Department of DermatologyResearch Institute for Tropical MedicineMetro ManilaPhilippines
  2. 2.Department of Internal MedicineDe La Salle Health Sciences InstituteCavitePhilippines
  3. 3.Department of DermatologyFiona Stanley Hospital and University of Western AustraliaPerthAustralia

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