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Noninfectious Granulomas in Pigmented Skin

  • Nour Kibbi
  • Abdul-Ghani Kibbi
Chapter

Abstract

Granulomatous skin diseases are a diverse group of disorders as chronic inflammatory responses to infectious and noninfectious antigens and/or other organic or inorganic materials the immune system is unable to eliminate. The diagnosis of granulomatous diseases relies heavily on clinical and pathological examination; the unifying finding is an inflammatory infiltrate predominantly composed of histiocytes, macrophages, and giant cells, sometimes showing collagen degeneration and caseation necrosis. The clinical manifestations are generally rare and may differ in their incidence and presentation in individuals with heavily pigmented ethnic skin.

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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of DermatologyYale UniversityNew HavenUSA
  2. 2.Department of DermatologyAmerican University of Beirut Medical CenterBeirutLebanon

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