Introduction to Retroperitoneal Tumors
Retroperitoneal sarcomas (RPS) present specific therapeutic challenges because of their location and frequent close association with several vital structures in the retroperitoneum. This proximity to major vessels, visceral organs, axial skeleton, and neural structures may significantly impair the ability to perform a margin-negative resection, which is the single potentially curative treatment approach in patients who have localized disease. Even in the setting of a complete resection, local recurrence is common.
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