MR Findings of Rectal Carcinoma

  • Sofia N. Gourtsoyianni


Magnetic resonance imaging (MRI) plays a pivotal role in rectal cancer treatment.


  1. 1.
    Beets-Tan RG, Lambregts DM, Maas M et al (2013) Magnetic resonance imaging for the clinical management of rectal cancer patients: recommendations from the 2012 European Society of Gastrointestinal and Abdominal Radiology (ESGAR) consensus meeting. Eur Radiol 23(9):2522–2531CrossRefGoogle Scholar
  2. 2.
    Tudyka V, Blomqvist L, Beets-Tan RG et al (2014) EURECCA consensus conference highlights about colon & rectal cancer multidisciplinary management: the radiology experts review. Eur J Surg Oncol 40(4):469–475CrossRefGoogle Scholar
  3. 3.
    Bipat S, Glas AS, Slors FJ, Zwinderman AH, Bossuyt PM, Stoker J (2004) Rectal cancer: local staging and assessment of lymph node involvement with endoluminal US, CT, and MR imaging- a meta-analysis. Radiology 232(3):773–783CrossRefGoogle Scholar
  4. 4.
    MERCURY Study Group (2006) Diagnostic accuracy of preoperative magnetic resonance imaging in predicting curative resection of rectal cancer: prospective observational study. BMJ 333:779CrossRefGoogle Scholar
  5. 5.
    Pahlman L (2000) Neoadjuvant and adjuvant radio- and radio-chemotherapy of rectal carcinomas. Int J Color Dis 15:1–8CrossRefGoogle Scholar
  6. 6.
    Wibe A, Rendedal P, Svensson E et al (2002) Prognostic significance of the circumferential resection margin following total mesorectal excision for rectal cancer. Br J Surg 89:327–334CrossRefGoogle Scholar
  7. 7.
    Quirke P, Durdey P, Dixon MF et al (1986) Local recurrence of rectal adenocarcinoma due to inadequate surgical resection. Histopathological study of lateral tumor spread and surgical excision. Lancet 2:996–999CrossRefGoogle Scholar
  8. 8.
    Heald RJ, Ryall RD (1986) Recurrence and survival after total mesorectal excision for rectal cancer. Lancet 1:1479–1482CrossRefGoogle Scholar
  9. 9.
    Kapiteijn E, Marijnen C, Nagtegaal I et al (2001) Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer. N Engl J Med 345:638–646CrossRefGoogle Scholar
  10. 10.
    Beets-Tan RG, Beets GL (2004) Rectal cancer: review with emphasis on MR imaging. Radiology 232(2):335–346CrossRefGoogle Scholar
  11. 11.
    Hermanek P, Guggenmoos-Holzmann I, Gall FP (1989) Prognostic factors in rectal carcinoma. A contribution to the further development of tumor classification. Dis Colon Rectum 32(7):593–599CrossRefGoogle Scholar
  12. 12.
    Gunderson LL, Sargent DJ, Tepper JE et al (2004) Impact of T and N stage and treatment on survival and relapse in adjuvant rectal cancer: a pooled analysis. J Clin Oncol 22(10):1785–1796CrossRefGoogle Scholar
  13. 13.
    Lindmark G, Gerdin B, Påhlman L, Bergström R, Glimelius B (1994) Prognostic predictors in colorectal cancer. Dis Colon Rectum 37(12):1219–1227CrossRefGoogle Scholar
  14. 14.
    Cawthorn SJ, Parums DV, Gibbs NM et al (1990) Extent of mesorectal spread and involvement of lateral resection margin as prognostic factors after surgery for rectal cancer. Lancet 335(8697):1055–1059CrossRefGoogle Scholar
  15. 15.
    Merkel S, Mansmann U, Siassi M, Papadopoulos T, Hohenberger W, Hermanek P (2001) The prognostic inhomogeneity in pT3 rectal carcinomas. Int J Color Dis 16(5):298–304CrossRefGoogle Scholar
  16. 16.
    Shepherd NA, Baxter KJ, Love SB (1997) The prognostic importance of peritoneal involvement in colonic cancer: a prospective evaluation. Gastroenterology 112(4):1096–1102CrossRefGoogle Scholar
  17. 17.
    Beets-Tan RG, Beets GL, Vliegen RF et al (2001) Accuracy of magnetic resonance imaging in prediction of tumor free resection margin in rectal cancer surgery. Lancet 357(9255):497–504CrossRefGoogle Scholar
  18. 18.
    Engelen SM, Beets-Tan RG, Lahaye MJ, Kessels AG, Beets GL (2008) Location of involved mesorectal and extramesorectal lymph nodes in patients with primary rectal cancer: preoperative assessment with MR imaging. Eur J Surg Oncol 34(7):776–781CrossRefGoogle Scholar
  19. 19.
    Will O, Purkayasthas S, Chan C et al (2005) Diagnostic precision of nanoparticle – enhanced MRI for lymph-node metastases: a meta-analysis. Lancet Oncol 7:52–60CrossRefGoogle Scholar
  20. 20.
    Brown G, Richards CJ, Bourne MW et al (2003) Morphologic predictors of lymph node status in rectal cancer with use of high-spatial-resolution MR imaging with histopathologic comparison. Radiology 227(2):371–377CrossRefGoogle Scholar
  21. 21.
    Lambregts DM, Heijnen LA, Maas M et al (2013) Gadofosveset-enhanced MRI for the assessment of rectal cancer lymph nodes: predictive criteria. Abdom Imaging 38(4):720–727CrossRefGoogle Scholar
  22. 22.
    Brown G (2008) Staging rectal cancer: endoscopic ultrasound and pelvic MRI. Cancer Imaging 8(Suppl A):S43–S45CrossRefGoogle Scholar
  23. 23.
    Smith NJ, Barbachano Y, Norman AR, Swift RI, Abulafi AM, Brown G (2008) Prognostic significance of magnetic resonance imaging-detected extramural vascular invasion in rectal cancer. Br J Surg 95(2):229–236CrossRefGoogle Scholar
  24. 24.
    Bugg WG, Andreou AK, Biswas D, Toms AP, Williams SM (2014) The prognostic significance of MRI-detected extramural venous invasion in rectal carcinoma. Clin Radiol 69(6):619–623CrossRefGoogle Scholar
  25. 25.
    Habr-Gama A (2006) Assessment and management of the complete clinical response of rectal cancer to chemoradiotherapy. Color Dis 8(Suppl 3):21–24CrossRefGoogle Scholar
  26. 26.
    Huh JW, Park YA, Jung EJ, Lee KY, Sohn SK (2008) Accuracy of endorectal ultrasonography and computed tomography for restaging rectal cancer after preoperative chemoradiation. J Am Coll Surg 207(1):7–12CrossRefGoogle Scholar
  27. 27.
    Vliegen RF, Beets GL, Lammering G et al (2008) Mesorectal fascia invasion after neoadjuvant chemotherapy and radiation therapy for locally advanced rectal cancer: accuracy of MR imaging for prediction. Radiology 246(2):454–462CrossRefGoogle Scholar
  28. 28.
    Taylor FG, Swift RI, Blomqvist L, Brown G (2008) A systematic approach to the interpretation of preoperative staging MRI for rectal cancer. AJR Am J Roentgenol 191(6):1827–1835CrossRefGoogle Scholar
  29. 29.
    Dworak O, Keilholz L, Hoffmann A (1997) Pathological features of rectal cancer after preoperative radiochemotherapy. Int J Colorectal Dis 12(1):19–23CrossRefGoogle Scholar
  30. 30.
    Park MJ, Kim SH, Lee SJ, Jang KM, Rhim H (2011) Locally advanced rectal cancer: added value of diffusion-weighted MR imaging for predicting tumor clearance of the mesorectal fascia after neoadjuvant chemotherapy and radiation therapy. Radiology 260(3):771–780CrossRefGoogle Scholar
  31. 31.
    Koh DM, Chau I, Tait D, Wotherspoon A, Cunningham D, Brown G (2008) Evaluating mesorectal lymph nodes in rectal cancer before and after neoadjuvant chemoradiation using thin-section T2-weighted magnetic resonance imaging. Int J Radiat Oncol Biol Phys 71(2):456–461CrossRefGoogle Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Sofia N. Gourtsoyianni
    • 1
  1. 1.Radiology Department, St. Thomas’ HospitalGuy’s & St Thomas’ NHS FTLondonUK

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