Positron Emission Tomography in Bone and Soft Tissue Tumors
Positron emission tomography/computed tomography with the use of 18F-fluorodeoxyglucose (18F-FDG PET/CT) is an imaging modality that combines both functional and anatomical information. The combination of PET with CT has been established as an imaging modality and is currently widely used in oncology. Bone and soft tissue tumors, as of course the majority of tumors, are characterized of multiple metabolic and molecular alterations, which allow imaging with positron emitters. These alterations include increased glucolysis, increased amino acid, and increased nucleic acid metabolic activity.