Echocardiography in Systemic Diseases

  • Azin Alizadehasl
  • Anita Sadeghpour


Cardiovascular disorders are a vital manifestation of systemic diseases and lead to substantial mortality and morbidity. Echocardiography has emerged as a useful noninvasive modality for the screening and evaluation of cardiac involvement in these cases. The technological developments in echocardiographic techniques and their concomitant advances in the recognition of subclinical diseases have ushered in a greater appreciation of the nature and prevalence of cardiac involvement in this group of patients. The present review explains cardiac involvement in patients with systemic lupus erythematosus, antiphospholipid antibody syndrome, Takayasu arteritis, and ankylosing spondylitis and introduces the role of different echocardiographic modalities in their evaluation.


Systemic diseases Echocardiography Systemic lupus erythematosus Antiphospholipid antibody syndrome Takayasu arteritis Ankylosing spondylitis 



Antiphospholipid syndrome


Aortic valve


Coronary artery disease


Mitral regurgitation


Mitral valve


Pulmonary hypertension


Rheumatoid arteritis


Systemic lupus erythematosus


Takayasu arteritis


Transesophageal echocardiography


Transthoracic echocardiography

Supplementary material

Movie 40.1

LV long axis view showing thickened MV leaflets (AVI 14922 kb)

Movie 40.2

LV long axis view showing thickened MV leaflets associated with moderate AR and moderate MR (AVI 7325 kb)

Movie 40.3

Short axis view (at the mitral valve level) showing thickening at the tips of the MV leaflets in a patient with systemic lupus erythematosus (SLE) (AVI 12285 kb)


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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Azin Alizadehasl
    • 1
  • Anita Sadeghpour
    • 2
  1. 1.Echocardiography and Cardiogenetic Research CentersCardio-Oncology Department, Rajaie Cardiovascular Medical and Research CenterTehranIran
  2. 2.Echocardiography Research Center, Rajaie Cardiovascular Medical and Research CenterIran University of Medical ScienceTehranIran

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