Cold Atmospheric Plasma in Context of Surgical Site Infection

  • Rico RutkowskiEmail author
  • Matthias Schuster
  • Julia Unger
  • Isabella Metelmann
  • Tran Thi Trung Chien


Based on an increasing understanding of cellular and molecular effects clinical use of cold atmospheric shows a constantly and rapidly expanding application horizon. In particular, the field of antimicrobial efficacy can reference to in vitro and in vitro assured treatment successes, opening up interdisciplinary approaches and potentials. Despite all medical advances, surgical site infections are among the most common nosocomial infections worldwide. While the typical causal pathogen spectrum depends on the type of surgery several endogenous and exogenous risk factors have been identified. The chapter provides an overview of selected prevention measures and illustrates current approaches to integrate cold atmospheric plasma into existing anti SSI prevention and therapy concepts. While there is still a need for further evidence-based research the interim evaluation demonstrates the comprehensive potential of cold atmospheric plasma in the fight against this kind of healthcare-associated nosocomial infection including all medical and economic challenges.


Cold atmospheric plasma Surgical site infection SSI Hyperspectral imaging HSI 


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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Rico Rutkowski
    • 1
    Email author
  • Matthias Schuster
    • 1
  • Julia Unger
    • 2
  • Isabella Metelmann
    • 3
  • Tran Thi Trung Chien
    • 4
  1. 1.Department of Oral and Maxillofacial Surgery/Plastic SurgeryUniversity Medicine GreifswaldGreifswaldGermany
  2. 2.Department of Obstetrics and GynecologyUniversity Medicine GreifswaldGreifswaldGermany
  3. 3.Department of Visceral, Vascular, Transplant and Thoracic SurgeryUniversity Medicine LeipzigLeipzigGermany
  4. 4.Vietnam Association of HIV/AIDS PreventionHanoiVietnam

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