Stem Cells in Oncoplastic Breast Surgery

  • Premrutai Thitilertdecha
  • Visnu Lohsiriwat


There are many types of stem cells including embryonic stem cells (ESCs), induced pluripotent stem cells (iPSCs), mesenchymal stem cells (MSCs), and tissue-specific stem cells; however, clinical applications of ESCs and iPSCs are limited due to ethical consideration and cell regulation. Tissue-specific stem cells are also not really accessible and still in controversial for their therapeutic potential. These, hence, make MSCs of great interest to the field of stem cell therapy. This chapter establishes fundamental knowledge of MSCs, particularly adipose-derived stem cells (ADSCs), and extensive information of isolation methods and surface antigenic profiling of human ADSCs as well as their multilineage differentiation capacity for potential utility in cell-based therapy. These comprehensive contents with scientific supports will help surgeons to better understand the basis of ADSCs and their functions before implementation into clinical practices.


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Copyright information

© Springer International Publishing AG, part of Springer Nature 2019

Authors and Affiliations

  • Premrutai Thitilertdecha
    • 1
    • 2
  • Visnu Lohsiriwat
    • 3
  1. 1.Research Group in Immunobiology and Therapeutic Sciences, Faculty of Medicine Siriraj HospitalMahidol UniversityBangkokThailand
  2. 2.Department of Research and Development, Faculty of Medicine Siriraj HospitalMahidol UniversityBangkokThailand
  3. 3.Faculty of Medicine, Department of Surgery, Siriraj HospitalMahidol UniversityBangkokThailand

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