Advertisement

The Use of Acellular Dermal Matrices in Implant-Based Breast Reconstruction

  • Glyn Jones
Chapter

Abstract

Implant-based techniques are the most widely used approaches to breast reconstruction of the world today. In the United States alone, they account for six times the number of reconstructions compared with all autologous reconstructive techniques combined. Two-stage expander-implant reconstruction is one of the most widely used forms of breast reconstruction, although single-stage direct-to-implant reconstruction is becoming increasingly popular. Despite the popularity of implant-based techniques, they have been fraught with the problems of capsular contracture, rippling of implants beneath the overlying thin skin envelope, and pseudoptosis of the device as the lower pole skin attenuates with time. Numerous solutions to these issues have been tried often with little success. During the past 14 years, acellular dermal matrices have been increasingly incorporated into implant-based reconstructions and appear to offer a degree of resolution to many of these troublesome issues.

Supplementary material

Video 38.1

(MP4 171700 kb)

Video 38.2

(MP4 171690 kb)

Suggested Reading

  1. 1.
    Ashikari RH, Ashikari AY, Kelemen PR et al (2008) Subcutaneous mastectomy and immediate reconstruction for prevention of breast cancer for high-risk patients. Breast Cancer 15:185PubMedCrossRefGoogle Scholar
  2. 2.
    Basu CB, Leong M, Hicks MJ (2010) Acellular cadaveric dermis decreases the inflammatory response in capsule formation in reconstructive breast surgery. Plast Reconstr Surg 126(6):1842–1847PubMedCrossRefGoogle Scholar
  3. 3.
    Baxter RA (2003) Intracapsular allogenic dermal grafts for breast implant-related problems. Plast Reconstr Surg 112:1692.; discussion 1697PubMedCrossRefGoogle Scholar
  4. 4.
    Becker S, Saint-Cyr M, Wong C et al (2009) AlloDerm versus DermaMatrix in immediate expander-based breast reconstruction: a preliminary comparison of complication profiles and material compliance. Plast Reconstr Surg 123(1):1–6.; discussion 107PubMedCrossRefGoogle Scholar
  5. 5.
    Bindingnavele V, Gaon M, Ota KS et al (2007) Use of acellular cadaveric dermis and tissue expansion in postmastectomy breast reconstruction. J Plast Reconstr Aesthet Surg 60:1214PubMedCrossRefGoogle Scholar
  6. 6.
    Boehmler JH IV, Butler CE, Ensor J et al (2009) Outcomes of various techniques of abdominal fascia closure after TRAM flap breast reconstruction. Plast Reconstr Surg 123:773PubMedCrossRefGoogle Scholar
  7. 7.
    Bökel C, Brown NH (2002) Integrins in development: moving on, responding to, and sticking to the extracellular matrix. Dev Cell 3:311PubMedCrossRefGoogle Scholar
  8. 8.
    Breuing KH, Colwell AS (2007) Inferolateral AlloDerm hammock for implant coverage in breast reconstruction. Ann Plast Surg 59:250PubMedCrossRefGoogle Scholar
  9. 9.
    Breuing KH, Warren SM (2005) Immediate bilateral breast reconstruction with implants and inferolateral AlloDerm slings. Ann Plast Surg 55:232PubMedCrossRefGoogle Scholar
  10. 10.
    Brigido SA (2006) The use of an acellular dermal regenerative tissue matrix in the treatment of lower extremity wounds: a prospective 16-week pilot study. Int Wound J 3:181PubMedCrossRefGoogle Scholar
  11. 11.
    Caplan AI (1991) Mesenchymal stem cells. J Orthop Res 9:641PubMedCrossRefGoogle Scholar
  12. 12.
    Colwell AS, Breuing KH (2008) improving shape and symmetry in mastopexy with autologous or cadaveric dermal slings. Ann Plast Surg 61:138PubMedCrossRefGoogle Scholar
  13. 13.
    Costantino PD, Govindaraj S, Hiltzik DH et al (2001) Acellular dermis for facial soft tissue augmentation: preliminary report. Arch Facial Plast Surg 3:38PubMedGoogle Scholar
  14. 14.
    Cothren CC, Gallego K, Anderson ED et al (2004) Chest wall reconstruction with acellular dermal matrix (AlloDerm) and a latissimus muscle flap. Plast Reconstr Surg 114:1015PubMedCrossRefGoogle Scholar
  15. 15.
    Disa JJ, Chiaramonte MF, Girotto JA et al (2001) Advantages of autologous fascia versus synthetic patch abdominal reconstruction in experimental animal defects. Plast Reconstr Surg 108:2086PubMedCrossRefGoogle Scholar
  16. 16.
    Disa JJ, McCarthy CM, Mehrara BJ et al (2008) Histologic analysis of angiogenesis and lymphangiogenesis in acellular human dermis. Plast Reconstr Surg 121:159ePubMedCrossRefGoogle Scholar
  17. 17.
    Dubin MG, Feldman M, Ibrahim HZ et al (2000) Allograft dermal implant (AlloDerm) in a previously irradiated field. Laryngoscope 110:934PubMedCrossRefGoogle Scholar
  18. 18.
    Eppley BL (2001) Experimental assessment of the revascularization of acellular human dermis for soft-tissue augmentation. Plast Reconstr Surg 107(3):757–762PubMedCrossRefGoogle Scholar
  19. 19.
    Gamboa-Bobadilla GM (2006) Implant breast reconstruction using acellular dermal matrix. Ann Plast Surg 56:22PubMedCrossRefGoogle Scholar
  20. 20.
    Garramone CE, Lam B (2007a) Use of AlloDerm in primary nipple reconstruction to improve long-term nipple projection. Plast Reconstr Surg 119:1663PubMedCrossRefGoogle Scholar
  21. 21.
    Garramone CE, Lam B (2007b) Use of AlloDerm in primary nipple reconstruction to improve long-term nipple projection. Plast Reconstr Surg 119:1663PubMedCrossRefGoogle Scholar
  22. 22.
    Glasberg SB, D’Amico RA (2006) Use of regenerative human acellular tissue (AlloDerm) to reconstruct the abdominal wall following pedicle TRAM flap breast reconstruction surgery. Plast Reconstr Surg 118:8PubMedCrossRefGoogle Scholar
  23. 23.
    Harper JR, McQuillan DJ (2007) A novel regenerative tissue matrix (RTM) technology for connective tissue reconstruction. Wounds 19:163PubMedGoogle Scholar
  24. 24.
    Holton LH, Haerian H, Silverman RP et al (2005) Improving long-term projection in nipple reconstruction using human acellular dermal matric: an animal model. Ann Plast Surg 55:304–309PubMedCrossRefGoogle Scholar
  25. 25.
    Holton LH III, Chung T, Silverman RP et al (2007) Comparison of acellular dermal matrix and synthetic mesh for lateral chest wall reconstruction in a rabbit model. Plast Reconstr Surg 119:1238PubMedCrossRefGoogle Scholar
  26. 26.
    Ibrahim HZ, Kwiatkowski TJ, Montone KT et al (2000) Effects of external beam radiation on the allograft dermal implant. Otolaryngol Head Neck Surg 122:189PubMedCrossRefGoogle Scholar
  27. 27.
    Jansen LA, Macadam SA (2011a) The use of AlloDerm in postmastectomy alloplastic breast reconstruction: part I. A systematic review. [Review]. Plast Reconstr Surg 127(6):2232–2244PubMedCrossRefGoogle Scholar
  28. 28.
    Jansen LA, Macadam SA (2011b) The use of AlloDerm in postmastectomy alloplastic breast reconstruction: part II. A cost analysis. [Review]. Plast Reconstr Surg 127(6):2245–2254PubMedCrossRefGoogle Scholar
  29. 29.
    Jin J, Rosen MJ, Blatnik J et al (2007) Use of acellular dermal matrix for complicated ventral hernia repair: does technique affect outcomes? J Am Coll Surg 205:654PubMedCrossRefGoogle Scholar
  30. 30.
    Jones GE, Harper A (2009) Technical advances in breast reconstruction in Bostwick’s Plastic and Reconstructive Breast Surgery, 3rd edn. Quality Medical Publishing, St. LouisGoogle Scholar
  31. 31.
    Liao EC, Breuing KH (2007) Breast mound salvage using vacuum-assisted closure device as bridge to reconstruction with inferolateral AlloDerm hammock. Ann Plast Surg 59:218PubMedCrossRefGoogle Scholar
  32. 32.
    Livesey S, Herndon D, Hollyoak M et al (1995) Transplanted acellular allograft dermal matrix. Transplantation 60(1):1–9PubMedCrossRefGoogle Scholar
  33. 33.
    Margulies AG, Hochberg J, Kepple J et al (2005) Total skin-sparing mastectomy without preservation of the nipple-areola complex. Am J Surg 190:907–912PubMedCrossRefGoogle Scholar
  34. 34.
    Mofid MM, Singh NK (2009) Pocket conversion made easy: a simple technique using AlloDerm to convert subglandular breast implants to the dual-plane position. Aesthet Surg J 29:12PubMedCrossRefGoogle Scholar
  35. 35.
    Nahabedian MY (2007) Does AlloDerm stretch? Plast Reconstr Surg 120:1276PubMedCrossRefGoogle Scholar
  36. 36.
    Nahabedian MY (2005) Secondary nipple reconstruction using local flaps and AlloDerm. Plast Reconstr Surg 115:2056PubMedCrossRefGoogle Scholar
  37. 37.
    Nahabedian MY (2009) AlloDerm performance in the setting of prosthetic breast surgery, infection and irradiation. Plast Reconstr Surg 124(6):1743–1753PubMedCrossRefGoogle Scholar
  38. 38.
    Otterburn D, Losken A (2009) The use of porcine acellular dermal material for TRAM flap donor-site closure. Plast Reconstr Surg 74e:123Google Scholar
  39. 39.
    Prantl L, Schreml S, Fichtner-Feigl S et al (2007) Clinical and morphological conditions in capsular contracture formed around silicone breast implants. Plast Reconstr Surg 120:275PubMedCrossRefGoogle Scholar
  40. 40.
    Preminger BA, McCarthy CM, Hu QY, Mehrara BJ, Disa JJ (2008a) The influence of AlloDerm on expander dynamics and complications in the setting of immediate tissue expander/implant reconstruction: a matched-cohort study. Ann Plast Surg 60:510PubMedCrossRefGoogle Scholar
  41. 41.
    Preminger BA, McCarthy CM, Hu QY, Mehrara BJ, Disa JJ (2008b) The influence of AlloDerm on expander dynamics and complications in the setting of immediate tissue expander/implant reconstruction: a matched-cohort study. Ann Plast Surg 60:510PubMedCrossRefGoogle Scholar
  42. 42.
    Salzberg CA (2006) Nonexpansive immediate breast reconstruction using human acellular tissue matrix graft (AlloDerm). Ann Plast Surg 57(1):1–5PubMedCrossRefGoogle Scholar
  43. 43.
    Silverman RP, Singh NK, Li EN et al (2004) Restoring abdominal wall integrity in contaminated tissue-deficient wounds using autologous fascia grafts. Plast Reconstr Surg 113:673PubMedCrossRefGoogle Scholar
  44. 44.
    Spear SL, Bedford SM (2007) Discussion of Saulis AS, Mustoe TA, Fine NA. A retrospective analysis of patient satisfaction with immediate postmastectomy breast reconstruction: comparison of three common procedures. Plast Reconstr Surg 119:1677CrossRefGoogle Scholar
  45. 45.
    Spear SL, Parikh PM, Reisin E et al (2008) Acellular dermis-assisted breast reconstruction. Aesthet Plast Surg 32:418CrossRefGoogle Scholar
  46. 46.
    Sigalove S, Maxwell GP, Sigalove NM, Storm-Dickerson TL, Pope N, Rice J, Gabriel A (2017) Prepectoral implant-based breast reconstruction: rationale, indications, and preliminary results. Plast Reconstr Surg 139(2):287–294PubMedCrossRefGoogle Scholar
  47. 47.
    Topol BM, Dalton EF, Ponn T et al (2008) Immediate single-stage breast reconstruction using implants and human acellular dermal tissue matrix with adjustment of the lower pole of the breast to reduce unwanted lift. Ann Plast Surg 61:494PubMedCrossRefGoogle Scholar
  48. 48.
    Zienowicz RJ, Karacaoglu E (2007) Implant-based breast reconstruction with allograft. Plast Reconstr Surg 120:373PubMedCrossRefGoogle Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2019

Authors and Affiliations

  • Glyn Jones
    • 1
  1. 1.Department of Plastic SurgeryProctor HospitalPeoriaUSA

Personalised recommendations