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Exercise Therapy and Cardiovascular Benefits in Patients with Cancer

  • Amy M. Berkman
  • Susan C. Gilchrist
Chapter

Abstract

Exercise therapy improves vascular function and survival. In this chapter we briefly review the benefits of exercise therapy in patients with cancer.

Keywords

Exercise therapy Cardiovascular Cancer 

References

  1. 1.
    Lenihan DJ, Cardinale DM. Late cardiac effects of cancer treatment. J Clin Oncol. 2012;30:3657–64.CrossRefPubMedGoogle Scholar
  2. 2.
    Mason C, Alfano CM, Smith AW, Wang CY, Neuhouser ML, Duggan C, Bernstein L, Baumgartner KB, Baumgartner RN, Ballard-Barbash R, McTiernan A. Long-term physical activity trends in breast cancer survivors. Cancer Epidemiol Biomark Prev. 2013;22:1153–61.CrossRefGoogle Scholar
  3. 3.
    Jack S, West MA, Raw D, Marwood S, Ambler G, Cope TM, Shrotri M, Sturgess RP, Calverley PM, Ottensmeier CH, Grocott MP. The effect of neoadjuvant chemotherapy on physical fitness and survival in patients undergoing oesophagogastric cancer surgery. Eur J Surg Oncol. 2014;40:1313–20.CrossRefPubMedGoogle Scholar
  4. 4.
    Lyman GH, Bohlke K, Falanga A, American Society of Clinical Oncology. Venous thromboembolism prophylaxis and treatment in patients with cancer: American Society of Clinical Oncology clinical practice guideline update. J Oncol Pract. 2015;11:e442–4.CrossRefPubMedGoogle Scholar
  5. 5.
    Seicean S, Seicean A, Plana JC, Budd GT, Marwick TH. Effect of statin therapy on the risk for incident heart failure in patients with breast cancer receiving anthracycline chemotherapy: an observational clinical cohort study. J Am Coll Cardiol. 2012;60:2384–90.CrossRefPubMedGoogle Scholar
  6. 6.
    Vejpongsa P, Yeh ET. Prevention of anthracycline-induced cardiotoxicity: challenges and opportunities. J Am Coll Cardiol. 2014;64:938–45.CrossRefPubMedGoogle Scholar
  7. 7.
    Liu H, Wang H, Xiang D, Guo W. Pharmaceutical measures to prevent doxorubicin-induced cardiotoxicity. Mini Rev Med Chem. 2017;17:44–50.CrossRefPubMedGoogle Scholar
  8. 8.
    Clark AM, Hartling L, Vandermeer B, McAlister FA. Meta-analysis: secondary prevention programs for patients with coronary artery disease. Ann Intern Med. 2005;143:659–72.CrossRefPubMedGoogle Scholar
  9. 9.
    Adamopoulos S, Schmid JP, Dendale P, Poerschke D, Hansen D, Dritsas A, Kouloubinis A, Alders T, Gkouziouta A, Reyckers I, Vartela V, Plessas N, Doulaptsis C, Saner H, Laoutaris ID. Combined aerobic/inspiratory muscle training vs. aerobic training in patients with chronic heart failure: the Vent-HeFT trial: a European prospective multicentre randomized trial. Eur J Heart Fail. 2014;16:574–82.CrossRefPubMedGoogle Scholar
  10. 10.
    Goldstein LB. Physical activity and the risk of stroke. Expert Rev Neurother. 2010;10:1263–5.CrossRefPubMedGoogle Scholar
  11. 11.
    Faulkner J, Lambrick D, Woolley B, Stoner L, Wong LK, McGonigal G. Effects of early exercise engagement on vascular risk in patients with transient ischemic attack and nondisabling stroke. J Stroke Cerebrovasc Dis. 2013;22:e388–96.CrossRefPubMedGoogle Scholar
  12. 12.
    Lockard MM, Gopinathannair R, Paton CM, Phares DA, Hagberg JM. Exercise training-induced changes in coagulation factors in older adults. Med Sci Sports Exerc. 2007;39:587–92.CrossRefPubMedGoogle Scholar
  13. 13.
    Slentz CA, Duscha BD, Johnson JL, Ketchum K, Aiken LB, Samsa GP, Houmard JA, Bales CW, Kraus WE. Effects of the amount of exercise on body weight, body composition, and measures of central obesity: STRRIDE–a randomized controlled study. Arch Intern Med. 2004;164:31–9.CrossRefPubMedGoogle Scholar
  14. 14.
    Giannaki CD, Aphamis G, Sakkis P, Hadjicharalambous M. Eight weeks of a combination of high intensity interval training and conventional training reduce visceral adiposity and improve physical fitness: a group-based intervention. J Sports Med Phys Fitness. 2016;56:483–90.PubMedGoogle Scholar
  15. 15.
    Baster T, Baster-Brooks C. Exercise and hypertension. Aust Fam Physician. 2005;34:419–24.PubMedGoogle Scholar
  16. 16.
    Giallauria F, Vitelli A, Maresca L, Santucci De Magistris M, Chiodini P, Mattiello A, Gentile M, Mancini M, Grieco A, Russo A, Lucci R, Torella G, Berrino F, Panico S, Vigorito C. Exercise training improves cardiopulmonary and endothelial function in women with breast cancer: findings from the Diana-5 dietary intervention study. Intern Emerg Med. 2016;11:183–9.CrossRefPubMedGoogle Scholar
  17. 17.
    Gilbert SE, Tew GA, Fairhurst C, Bourke L, Saxton JM, Winter EM, Rosario DJ. Effects of a lifestyle intervention on endothelial function in men on long-term androgen deprivation therapy for prostate cancer. Br J Cancer. 2016;114:401–8.CrossRefPubMedPubMedCentralGoogle Scholar
  18. 18.
    Demark-Wahnefried W, Case LD, Blackwell K, Marcom PK, Kraus W, Aziz N, Snyder DC, Giguere JK, Shaw E. Results of a diet/exercise feasibility trial to prevent adverse body composition change in breast cancer patients on adjuvant chemotherapy. Clin Breast Cancer. 2008;8:70–9.CrossRefPubMedGoogle Scholar
  19. 19.
    Devin JL, Sax AT, Hughes GI, Jenkins DG, Aitken JF, Chambers SK, Dunn JC, Bolam KA, Skinner TL. The influence of high-intensity compared with moderate-intensity exercise training on cardiorespiratory fitness and body composition in colorectal cancer survivors: a randomised controlled trial. J Cancer Surviv. 2016;10:467–79.CrossRefPubMedGoogle Scholar
  20. 20.
    Dunne DF, Jack S, Jones RP, Jones L, Lythgoe DT, Malik HZ, Poston GJ, Palmer DH, Fenwick SW. Randomized clinical trial of prehabilitation before planned liver resection. Br J Surg. 2016;103:504–12.CrossRefPubMedGoogle Scholar
  21. 21.
    Courneya KS, McKenzie DC, Mackey JR, Gelmon K, Friedenreich CM, Yasui Y, Reid RD, Cook D, Jespersen D, Proulx C, Dolan LB, Forbes CC, Wooding E, Trinh L, Segal RJ. Effects of exercise dose and type during breast cancer chemotherapy: multicenter randomized trial. J Natl Cancer Inst. 2013;105:1821–32.CrossRefPubMedGoogle Scholar
  22. 22.
    Wood WA, Phillips B, Smith-Ryan AE, Wilson D, Deal AM, Bailey C, Meeneghan M, Reeve BB, Basch EM, Bennett AV, Shea TC, Battaglini CL. Personalized home-based interval exercise training may improve cardiorespiratory fitness in cancer patients preparing to undergo hematopoietic cell transplantation. Bone Marrow Transplant. 2016;51:967–72.CrossRefPubMedPubMedCentralGoogle Scholar
  23. 23.
    Schmitt J, Lindner N, Reuss-Borst M, Holmberg HC and Sperlich B. A 3-week multimodal intervention involving high-intensity interval training in female cancer survivors: a randomized controlled trial. Physiol Rep. 2016;4. pii: e12693.CrossRefPubMedPubMedCentralGoogle Scholar
  24. 24.
    Robsahm TE, Falk RS, Heir T, Sandvik L, Vos L, Erikssen JE, Tretli S. Measured cardiorespiratory fitness and self-reported physical activity: associations with cancer risk and death in a long-term prospective cohort study. Cancer Med. 2016;5:2136–44.CrossRefPubMedPubMedCentralGoogle Scholar
  25. 25.
    Lakoski SG, Willis BL, Barlow CE, Leonard D, Gao A, Radford NB, Farrell SW, Douglas PS, Berry JD, DeFina LF, Jones LW. Midlife cardiorespiratory fitness, incident cancer, and survival after cancer in men: the Cooper Center Longitudinal Study. JAMA Oncol. 2015;1:231–7.CrossRefPubMedPubMedCentralGoogle Scholar
  26. 26.
    Sawada SS, Lee IM, Naito H, Kakigi R, Goto S, Kanazawa M, Okamoto T, Tsukamoto K, Muto T, Tanaka H, Blair SN. Cardiorespiratory fitness, body mass index, and cancer mortality: a cohort study of Japanese men. BMC Public Health. 2014;14:1012.CrossRefPubMedPubMedCentralGoogle Scholar
  27. 27.
    Schmid D, Leitzmann MF. Cardiorespiratory fitness as predictor of cancer mortality: a systematic review and meta-analysis. Ann Oncol. 2015;26:272–8.CrossRefPubMedGoogle Scholar
  28. 28.
    Jones LW, Watson D, Herndon JE II, Eves ND, Haithcock BE, Loewen G, Kohman L. Peak oxygen consumption and long-term all-cause mortality in nonsmall cell lung cancer. Cancer. 2010;116:4825–32.CrossRefPubMedPubMedCentralGoogle Scholar
  29. 29.
    Jones LW, Courneya KS, Mackey JR, Muss HB, Pituskin EN, Scott JM, Hornsby WE, Coan AD, Herndon JE II, Douglas PS, Haykowsky M. Cardiopulmonary function and age-related decline across the breast cancer survivorship continuum. J Clin Oncol. 2012;30:2530–7.CrossRefPubMedPubMedCentralGoogle Scholar
  30. 30.
    Jones LW, Eves ND, Haykowsky M, Joy AA, Douglas PS. Cardiorespiratory exercise testing in clinical oncology research: systematic review and practice recommendations. Lancet Oncol. 2008;9:757–65.CrossRefPubMedGoogle Scholar
  31. 31.
    Silver JK. Cancer prehabilitation and its role in improving health outcomes and reducing health care costs. Semin Oncol Nurs. 2015;31:13–30.CrossRefPubMedGoogle Scholar
  32. 32.
    Jones LW, Peddle CJ, Eves ND, Haykowsky MJ, Courneya KS, Mackey JR, Joy AA, Kumar V, Winton TW, Reiman T. Effects of presurgical exercise training on cardiorespiratory fitness among patients undergoing thoracic surgery for malignant lung lesions. Cancer. 2007;110:590–8.CrossRefPubMedGoogle Scholar
  33. 33.
    Schmitz KH, Holtzman J, Courneya KS, Masse LC, Duval S, Kane R. Controlled physical activity trials in cancer survivors: a systematic review and meta-analysis. Cancer Epidemiol Biomark Prev. 2005;14:1588–95.CrossRefGoogle Scholar
  34. 34.
    Fong DY, Ho JW, Hui BP, Lee AM, Macfarlane DJ, Leung SS, Cerin E, Chan WY, Leung IP, Lam SH, Taylor AJ, Cheng KK. Physical activity for cancer survivors: meta-analysis of randomised controlled trials. BMJ. 2012;344:e70.CrossRefPubMedPubMedCentralGoogle Scholar
  35. 35.
    Jarvela LS, Kemppainen J, Niinikoski H, Hannukainen JC, Lahteenmaki PM, Kapanen J, Arola M, Heinonen OJ. Effects of a home-based exercise program on metabolic risk factors and fitness in long-term survivors of childhood acute lymphoblastic leukemia. Pediatr Blood Cancer. 2012;59:155–60.CrossRefPubMedGoogle Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.University of Vermont School of Medicine, University of VermontBurlingtonUSA
  2. 2.Department of Clinical Cancer Prevention and CardiologyThe University of Texas M.D. Anderson Cancer CenterHoustonUSA

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