Vulvar Disease pp 301-302 | Cite as

Methicillin-Resistant Staphylococcus aureus

  • Sara Wood


Skin and soft tissue infections (SSTIs) and abscesses at the vulva, vagina, groin, breast, and postoperative wounds are vulvar manifestations of methicillin-resistant Staphylococcus aureus (MRSA) infections. Nearly two-thirds of cultures revealed MRSA. Trimethoprim-sulfamethoxazole (TMP-SMX) is largely effective against MRSA along with other common vulvar abscess microbes, such as Proteus, Escherichia coli, and group B streptococcus. Decolonization includes nasal decolonization with mupirocin and topical body decolonization with skin disinfectants. Oral antibiotics for decolonization have not been shown to be efficacious unless an active infection is present.


  1. 1.
    Gordon R, Lowy F. Pathogenesis of methicillin-resistant Staphylococcus aureus infection. Clin Infect Dis. 2008;46:S350–9.CrossRefGoogle Scholar
  2. 2.
    Kilpatrick C, Alagkiozidis I, Orejuela F, et al. Factors complicating surgical management of the vulvar abscess. J Reprod Med. 2010;55(3–4):139–42.PubMedGoogle Scholar
  3. 3.
    Thurman A, Satterfield T, Soper D. Methicillin-resistant Staphylococcus aureus as a common cause of vulvar abscesses. Obstet Gynecol. 2008;112(3):538–44.CrossRefGoogle Scholar
  4. 4.
    Liu C, Bayer A, Cosgrove S, et al. Clinical practice guidelines by the Infectious Diseases Society of America for the treatment of methicillin-resistant Staphylococcus aureus infections in adults and children: executive summary. Clin Infect Dis. 2011;52(3):285–92.CrossRefGoogle Scholar
  5. 5.
    Stevens D, Bisno A, Chambers H, et al. Practice guidelines for the diagnosis and management of skin and soft tissue infections: 2014 update by the Infectious Diseases Society of America. Clin Infect Dis. 2014;59(2):e10–52.CrossRefGoogle Scholar
  6. 6.
    Breen J. Skin and soft tissue infections in immunocompetent patients. Am Fam Physician. 2010;81(7):893–9.PubMedGoogle Scholar
  7. 7.
    Wood S. Clinical manifestations and therapeutic management of vulvar cellulitis and abscess: methicillin-resistant Staphylococcus aureus, necrotizing fasciitis bartholin abscess, crohn disease of the vulva, hidradenitis suppurativa. Clin Obstet Gynecol. 2015;58(3):503–11.CrossRefGoogle Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2019

Authors and Affiliations

  • Sara Wood
    • 1
  1. 1.Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics and GynecologyMercy Hospital St. LouisSt. LouisUSA

Personalised recommendations