Factor V Leiden and Prothrombin Mutation: Common Thrombophilias

  • James P. R. BrownEmail author
  • Joanne Douglas


This chapter discusses the common inherited thrombophilias: factor V Leiden and prothrombin gene mutation. The chapter describes the epidemiology and pathophysiology of factor V Leiden and prothrombin gene mutation and states how the disorders affect pregnancy. The peripartum medical and anesthetic management of women with these conditions is discussed.


Factor V Leiden Prothrombin mutation G20210A Inherited thrombophilia 


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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.UBC Department of Anesthesiology, Pharmacology and TherapeuticsBC Women’s HospitalVancouverCanada
  2. 2.Department of AnesthesiaBC Women’s HospitalVancouverCanada

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