Factor V and Combined Factor V and VIII Deficiency

  • James P. R. BrownEmail author
  • Joanne Douglas


This chapter outlines the pathophysiology, clinical presentation, inheritance and incidence of factor V deficiency and combined factors V and VIII deficiency. The chapter describes the interaction with pregnancy and discusses the medical and anesthetic management of pregnant women with factor V deficiency or combined factors V and VIII deficiency.


Factor V deficiency Owren disease Parahemophilia Combined factor V and factor VIII deficiency Inherited coagulopathy Factor V Factor VIII Combined factor V and factor VIII 


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© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.UBC Department of Anesthesiology, Pharmacology and TherapeuticsBC Women’s HospitalVancouverCanada
  2. 2.Department of AnesthesiaBC Women’s HospitalVancouverCanada

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