Prothrombin (Factor II) Deficiency

  • James P. R. BrownEmail author
  • Joanne Douglas


This chapter outlines the pathophysiology, clinical presentation, inheritance, and incidence of prothrombin deficiency. The chapter describes the interaction with pregnancy and discusses the medical and anesthetic management of pregnant women with prothrombin deficiency, including treatment of acute hemorrhage.


Prothrombin deficiency Factor II 


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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.UBC Department of Anesthesiology, Pharmacology and TherapeuticsBC Women’s HospitalVancouverCanada
  2. 2.Department of AnesthesiaBC Women’s HospitalVancouverCanada

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