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Progenitor Skin Cell Therapy and Evolution of Medical Applications

  • Lee Ann Applegate
  • Paris Jafari
  • Corinne Scaletta
  • Anthony de Buys Roessingh
  • Wassim Raffoul
  • Nathalie Hirt-Burri
Chapter

Abstract

Organs and cells can be efficiently used and transformed into intermediate or final products that propose many advances in new medical technology from skin grafting to 3D micro-tissues for biocompatibility and industry testing. For instance, cell sources that can be easily expanded and stocked from allogeneic sources would be interesting in order to avoid the biopsy from the patient and the time necessary to prepare the cells before treatments of patients. Also, cell sources used historically in medicine can provide enough banked cells not only designated for treatment of patients but also for developing innovative testing platforms with uniform primary cell populations.

Keywords

Progenitor cells Stem cells Burns Musculoskeletal medicine Transplantation Cell bank Mesenchymal stem cell Hemostatic dressing Antimicrobial 

Abbreviations

AFIRM

Armed Forces Institute of Regenerative Medicine

BM-MSC

Bone marrow mesenchymal stem cell

DOD

Department of Defense

GMP

Good manufacturing Practice

GvHD

Graft versus host disease

MCB

Master cell bank

WCB

Working cell bank

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Copyright information

© Springer International Publishing AG 2017

Authors and Affiliations

  • Lee Ann Applegate
    • 1
  • Paris Jafari
    • 1
  • Corinne Scaletta
    • 1
  • Anthony de Buys Roessingh
    • 2
  • Wassim Raffoul
    • 1
  • Nathalie Hirt-Burri
    • 1
  1. 1.Department of Musculoskeletal Medicine, Plastic, Reconstructive and Hand Surgery, Unit of Regenerative TherapyUniversity Hospital of LausanneEpalingesSwitzerland
  2. 2.Department of Pediatric SurgeryUniversity Hospital of LausanneLausanneSwitzerland

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