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Acne Research Models

  • Gerd Plewig
  • Bodo Melnik
  • WenChieh Chen
Chapter

Abstract

Genuine acne is a disease singular to man and practically does not occur in animals. There are a few exceptions to this rule. Except for minor forms in dogs and cats, acne does not occur spontaneously in any animal species. Acne is a uniquely human disorder. Certain species possess sebaceous-like follicles and are suitable for assessing the comedogenicity of chemicals, the comedolytic effects of drugs, and the androgen metabolism of sebocytes. We recognize the limitations; yet these models have proved to be valuable both in research and in pharmacological testing.

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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Gerd Plewig
    • 1
  • Bodo Melnik
    • 2
  • WenChieh Chen
    • 3
  1. 1.Department of Dermatology and AllergyLudwig-Maximilian-University MunichMunichGermany
  2. 2.Department of Dermatology, Environmental Medicine and Health TheoryUniversity of OsnabrückOsnabrückGermany
  3. 3.Department of Dermatology and AllergyTechnical University of MunichMunichGermany

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