Ethical Principles in Healthcare Research

  • P. Anne ScottEmail author


Ethical issues permeate the entire research process from the identification of the research question and selection of research participants, to dissemination of findings. This chapter identifies some of the historical influences informing the development of research ethics frameworks internationally. The author then moves to highlight some of the key ethical issues that need to be considered throughout the various elements of the research process. Some of the important principles underlying research ethics frameworks are identified and interpreted within the context of the research process.


Nursing research Research ethics Respect for persons Autonomy Beneficence Informed consent 


  1. Adams M (1996) Final report on the tuskegee syphilis study 1932–1972. Accessed 25 Sept 2016
  2. Annas GJ, Grodin MA (eds) (1992) The Nazi doctors and the Nuremburg Code: human rights in human experimentation. The Nuremburg Code. Oxford University Press, New YorkGoogle Scholar
  3. Beauchamp TL, Childress JF (2013) Principles of biomedical ethics, 7th edn. Oxford University Press, New YorkGoogle Scholar
  4. Cartwright S (1988) The Report of the Committee of Inquiry into allegations concerning the treatment of Cervical Cancer at National Women’s Hospital and into other related matters. Accessed 25 Sept 2016
  5. Council of Europe (1997) Convention for protection of human rights and dignity of the human being with regard to the application of biology and medicine: convention on human rights and biomedicine. Oneda, 4.IV, European Treaty Series. European Commission. Accessed 25 Sept 2016
  6. De Raeve L (ed) (1996) Nursing research: an ethical and legal appraisal. Balliere-Tindall, LondonGoogle Scholar
  7. Doyal L, Tobias JS (eds) (2001) Informed consent in medical research. BMJ Group, LondonGoogle Scholar
  8. Government of Ireland (2006) Report on post mortem practice and procedures. Chair Dr Deirdre Madden. Stationary Office. DublinGoogle Scholar
  9. Hobson D (2003) Moral silence? Nurses experience of ethical decision making at the end of life. Unpublished PhD Thesis; City University, LondonGoogle Scholar
  10. International Council of Nurses (1996) Ethical guidelines for nursing research. ICN, GenevaGoogle Scholar
  11. Irish Council for Bioethics (2004) Operational procedures for research ethics committees: guidance. Irish Council for Bioethics, Dublin. Accessed 24 Sept 2016
  12. Kass NE, Sugarman J, Faden R, Schoch-Spana M (1996) Trust: the fragile foundations of contemporary biomedical research. Hastings Centre Report. Hastings Centre, New YorkGoogle Scholar
  13. Krugman S (1986) The Willowbrook hepatitis studies revisited: ethical aspects. Rev Infect Dis 8(1):157–162CrossRefGoogle Scholar
  14. Mason JK, McCall Smith RA (2010) Law and medical ethics, 8th edn. Butterworth, LondonGoogle Scholar
  15. Northern Nurses Federation (1995) Ethical guidelines for nursing research in the nordic countries. Sykepleiernes Sanarbeid i Norden, Oslo. Accessed 24 Sept 2016
  16. NMBI (2015) Ethical conduct in research: professional guidance. Nursing and Midwifery Board of Ireland, Dublin. Accessed 24 Sept 2016
  17. O’Mathúna DP (2012) Ethical considerations in designing intervention studies. In: Mazurek Melnyk B, Morrison-Beedy D (eds) Intervention research. Designing, conducting, analyzing, and funding: a practical guide for success. Springer Publishing, New York, pp 75–89Google Scholar
  18. Piasek P (2015) Case studies in therapeutic SenseCam use aimed at identity maintenance in early stage dementia. Unpublished PhD thesis, Dublin City University, DublinGoogle Scholar
  19. Paterson R (2010) The Cartwright legacy: shifting the focus of attention from the doctor to the patient. N Z Med J 123(1319):6–10PubMedGoogle Scholar
  20. Rawls J (1985) Justice as fairness: political not metaphysical. Philos Public Aff 14(3):223–251Google Scholar
  21. Royal College of Nurses (2011) Research ethics: RCN guidance for nurses, 3rd edn. Royal College of Nursing, London. Accessed 25 Sept 2016
  22. Scott PA (2006) Philosophy, nursing and the nature of evidence. In: Atkinson J, Crow M (eds) Interdisciplinary research: diverse approaches in science, technology and society. Wiley, ChichesterGoogle Scholar
  23. The Belmont Report: Principles and Guidelines for the Protection of Human Subjects of Research (1979) The National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research. US Government Printing Office, Washington, DC. Accessed 25 Sept 2016
  24. The Dunne Inquiry into organ retention in paediatric hospitals in the Republic of Ireland. Report submitted to the Tánaiste and Minister of Health, April 2005. UnpublishedGoogle Scholar
  25. The Royal Liverpool Children’s Inquiry Report (2001) Report on the removal, retention and disposal of human organs and tissues at Alder Hey children’s Hospital. Chair: Mr Michael Redfern, QC. HMSO, LondonGoogle Scholar
  26. United Nations (1948) The universal declaration of human rights. . Accessed 24 Sept 2016
  27. United Nations (1989) Convention on the rights of the child. Accessed 24 Sept 2016.
  28. World Medical Association (1964, 1975, 1983, 1989, 1996, 2000, 2002, 2004, 2008) Declaration of Helsinki: recommendations guiding physicians in biomedical research involving subjects. Accessed 24 Sept 2016

Copyright information

© Springer International Publishing AG 2017

Authors and Affiliations

  1. 1.National University of Ireland GalwayGalwayIreland

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