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Endoscopic Mucosal Dissection

  • Cigdem Benlice
  • Emre GorgunEmail author
Chapter

Abstract

Endoscopic submucosal dissection (ESD) is an innovative, advanced endoscopic approach to superficial gastrointestinal neoplasms which is becoming a “standard” treatment option and has the potential to revolutionize treatment of early alimentary cancers. Colorectal neoplasia represents an important potential niche for the clinical application of ESD in the United States given the prevalence of these tumors. ESD is a reliable but technically challenging method for en bloc resection of gastrointestinal lesions and requires dedicated equipment, a unique skill set, and experience.

Keywords

Endoscopic submucosal dissection (ESD) Submucosal injection solutions Snare types Endoknife Dual knife Hook knife 

Abbreviations

CT

Computerized tomography

EMR

Endoscopic mucosal resection

ESD

Endoscopic submucosal dissection

LCS

Laparoscopic colorectal surgery

SM

Submucosal invasion status

Supplementary material

Video 16.1

Combined endoscopic–laparoscopic surgery (CELS) (MP4 82012 kb)

References

  1. 1.
    Zauber AG, Winawer SJ, O'Brien MJ, et al. Colonoscopic polypectomy and long-term prevention of colorectal-cancer deaths. N Engl J Med. 2012;366(8):687–96.CrossRefPubMedPubMedCentralGoogle Scholar
  2. 2.
    Zhang M, Shin EJ. Successful endoscopic strategies for difficult polypectomy. Curr Opin Gastroenterol. 2013;29(5):489–894.PubMedGoogle Scholar
  3. 3.
    Gorgun E, Benlice C. Church J. Risk of cancer in endoscopically benign polyps unsuitable for endoscopic removal. Int J Colorectal Dis. 2014;57(5):E271–2.Google Scholar
  4. 4.
    Saito Y, Sakamoto T, Nakajima T, Matsuda T. Colorectal ESD: current indications and latest technical advances. Gastrointest Endosc Clin N Am. 2014;24(2):245–55.CrossRefPubMedGoogle Scholar
  5. 5.
    Gotoda T, Ho K, Soetikno R, Kaltenbach T, Draganov P. Gastric ESD: current status and future directions of devices and training. Gastrointest Endosc Clin N Am. 2014;24(2):213–33.CrossRefPubMedGoogle Scholar
  6. 6.
    Draganov PV, Gotoda T, Chavalitdhamrong D, Wallace MB. Techniques of endoscopic submucosal dissection: application for the western endoscopist? Gastrointest Endosc. 2013;78(5):677–88.CrossRefPubMedGoogle Scholar
  7. 7.
    Sanchez-Yague A, Kaltenbach T, Raju G, Soetikno R. Advanced endoscopic resection of colorectal lesions. Gastroenterol Clin North Am. 2013;42(3):459–77.CrossRefPubMedGoogle Scholar
  8. 8.
    Cohen J. A novel opportunity in minimally invasive colorectal cancer therapy: defining a role for endoscopic submucosal dissection in the United States. Diagn Ther Endosc. 2013;2013:681783.CrossRefPubMedPubMedCentralGoogle Scholar
  9. 9.
    Gorgun IE. Endoscopic instruments. In: Advanced colonoscopy. New York: Springer; 2014. p. 1–16.Google Scholar
  10. 10.
    Toyonaga T, Man M, Morita Y, Azuma T. Endoscopic submucosal dissection (ESD) versus simplified/hybrid ESD. Gastrointest Endosc Clin N Am. 2014;24(2):191–9.CrossRefPubMedGoogle Scholar
  11. 11.
    Repici A, Hassan C, Paula PD, et al. Efficacy and safety of endoscopic submucosal dissection for colorectal neoplasia: a systematic review. Endoscopy. 2012;44(2):137–50.CrossRefPubMedGoogle Scholar
  12. 12.
    Tanaka S, Terasaki M, Kanao H, Oka S, Chayama K. Current status and future perspectives of endoscopic submucosal dissection for colorectal tumors. Dig Endosc. 2012;24(s1):73–9.CrossRefPubMedGoogle Scholar
  13. 13.
    Lee E, Lee JB, Lee SH, Lee DH, Lee DS, Youk EG. Endoscopic submucosal dissection for colorectal tumors—1,000 colorectal ESD cases: one specialized institute’s experiences. Surg Endosc. 2013;27(1):31–9.CrossRefPubMedGoogle Scholar
  14. 14.
    Oka S, Tanaka S, Saito Y, et al. Local recurrence after endoscopic resection for large colorectal neoplasia: a multicenter prospective study in Japan. Am J Gastroenterol. 2015;110:697–707.CrossRefPubMedGoogle Scholar
  15. 15.
    Repici A, Pellicano R, Strangio G, Danese S, Fagoonee S, Malesci A. Endoscopic mucosal resection for early colorectal neoplasia: pathologic basis, procedures, and outcomes. Dis Colon Rectum. 2009;52(8):1502–15.CrossRefPubMedGoogle Scholar
  16. 16.
    Tanaka S, Kashida H, Saito Y, et al. JGES guidelines for colorectal endoscopic submucosal dissection/endoscopic mucosal resection. Dig Endosc. 2015;27(4):417–34.CrossRefPubMedGoogle Scholar
  17. 17.
    Tanaka S, Asayama N, Shigita K, Hayashi N, Oka S, Chayama K. Towards safer and appropriate application of endoscopic submucosal dissection for T1 colorectal carcinoma as total excisional biopsy: future perspectives. Dig Endosc. 2015;27(2):216–22.CrossRefPubMedGoogle Scholar
  18. 18.
    Kobayashi H, Mochizuki H, Morita T, et al. Characteristics of recurrence after curative resection for T1 colorectal cancer: Japanese multicenter study. J Gastroenterol. 2011;46(2):203–11.CrossRefPubMedGoogle Scholar
  19. 19.
    Kiriyama S, Saito Y, Yamamoto S, et al. Comparison of endoscopic submucosal dissection with laparoscopic-assisted colorectal surgery for early-stage colorectal cancer: a retrospective analysis. Endoscopy. 2012;44(11):1024–30.CrossRefPubMedGoogle Scholar

Copyright information

© Springer International Publishing AG 2017

Authors and Affiliations

  1. 1.Department of Colorectal SurgeryCleveland Clinic FoundationClevelandUSA
  2. 2.Department of Colorectal SurgeryDigestive Disease Institute, Cleveland Clinic FoundationClevelandUSA

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