Guyton at the Bedside

  • David Berlin
  • Vivek Moitra
  • Jan BakkerEmail author


This chapter describes the classic model of the circulation developed by Arthur Guyton and his team. The model envisions the circulation comprised of discrete components. The cardiac output is largely determined by the interactions of the venous return and the cardiac performance. The venous return is a function of the gradient between the mean systemic filling pressure and the right atrial pressure. The distribution of blood flow is largely controlled by autoregulation, thus matching oxygen demand and subsequently generating the venous return. Thus, cardiac output is a function of oxygen demand when cardiac function is not compromised. Caring for critically ill patient requires an understanding of Guytonian hemodynamics.


Physiology Hemodynamic monitoring Monitoring Resuscitation Fluid resuscitation Cardiac output Venous return 


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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Division of Pulmonary and Critical Care Medicine, Department of MedicineWeill Cornell Medical CollegeNew YorkUSA
  2. 2.Division of Critical Care, Department of AnesthesiologyCollege of Physicians and Surgeons of Columbia UniversityNew YorkUSA
  3. 3.Department of Intensive Care AdultsErasmus MC University Medical Center RotterdamRotterdamThe Netherlands
  4. 4.Departamento de Medicina Intensiva, Facultad de MedicinaPontificia Universidad Católica de ChileSantiagoChile
  5. 5.Division of Pulmonary and Critical Care MedicineCollege of Physicians and Surgeons of Columbia UniversityNew YorkUSA
  6. 6.Division of Pulmonary, Sleep Medicine and Critical CareNew York University, Langone Medical Center-Bellevue HospitalNew YorkUSA

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