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Proton Beam Therapy (For CNS Tumors)

  • Divya Yerramilli
  • Marc R. Bussière
  • Jay S. Loeffler
  • Helen A. Shih
Chapter

Abstract

For CNS tumors, proton beam therapy is a unique modality of radiation that offers several physical advantages as compared to traditional photon radiation. Protons have superior dose conformality and therefore significantly reduce normal tissue exposure to low dose radiation. This improved dosimetry translates into improved clinical outcomes for some indications of radiation therapy, and these scenarios will be further explored in this chapter. However, there are certain limitations to proton therapy, including the high capital costs and the lack of robust data on clinical applications. The true clinical benefit of proton therapy remains an active area of investigation, and ongoing studies to measure the potential reduction of treatment-related adverse effects will help to elucidate these controversies. In this chapter, the evolution, potential applications, and limitations of proton therapy will be described. Important treatment considerations, treatment planning, and quality assurance guidelines are also defined.

Keywords

Protons CNS tumors Radiation techniques Treatment planning Quality assurance 

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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Divya Yerramilli
    • 1
  • Marc R. Bussière
    • 2
  • Jay S. Loeffler
    • 2
  • Helen A. Shih
    • 2
  1. 1.Harvard Radiation Oncology Program, Department of Radiation OncologyMassachusetts General HospitalBostonUSA
  2. 2.Department of Radiation OncologyMassachusetts General HospitalBostonUSA

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