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Custom Indentation System for Mechanical Characterization of Soft Matter

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  • First Online:
Mechanics of Biological Systems and Materials, Volume 6

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Abstract

Soft, hydrated samples of biomaterials and live tissues are hard to characterize with standard equipment designed for engineering materials. To accommodate millimeter-scale samples with sub-kPa moduli, we designed a cantilever-based indentation system using piezoelectric actuators and capacitive sensors compatible with a variety of probe tips and sample holders. Embryonic mouse hearts, rat gastrointestinal tissues, human pancreas, and rat brain tissue have all been successfully characterized using this system.

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References

  1. Krick, B.A., Vail, J.R., Persson, B.N.J., Sawyer, W.G.: Optical in situ micro tribometer for analysis of real contact area for contact mechanics, adhesion, and sliding experiments. Tribol. Lett. 45(1), 185–194 (2011)

    Article  Google Scholar 

  2. Rubiano, A., Qi, Y., Guzzo, D., Rowe, K., Pepine, C., Simmons, C.: Stem cell therapy restores viscoelastic properties of myocardium in rat model of hypertension. J. Mech. Behav. Biomed. Mater. 59, 71–77 (2015)

    Article  Google Scholar 

  3. Hayes, W.C., Keer, L.M., Herrmann, G., Mockros, L.F.: A mathematical analysis for indentation tests of articular cartilage. J. Biomech. 5(5), 541–551 (1972)

    Article  Google Scholar 

  4. Moore, S.W., Keller, R.E., Koehl, M.A.: The dorsal involuting marginal zone stiffens anisotropically during its convergent extension in the gastrula of Xenopus laevis. Development 121(10), 3131–3140 (1995)

    Google Scholar 

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Acknowledgements

The authors would like to acknowledge research support from Medtronic (CSS) and the UF Institute for Cell & Tissue Science and Engineering (AR).

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Authors and Affiliations

  1. Department of Mechanical and Aerospace Engineering, University of Florida, 116250, Gainesville, FL, USA

    Chelsey Simmons & Andres Rubiano

  2. J. Crayton Pruitt Family Department of Biomedical Engineering, Herbert Wertheim College of Engineering, University of Florida, 116250, Gainesville, FL, USA

    Chelsey Simmons, Daniel Stewart & Brandey Andersen

  3. Division of Cardiovascular Medicine, Department of Medicine, College of Medicine, University of Florida, 116250, Gainesville, FL, USA

    Chelsey Simmons

Authors
  1. Chelsey Simmons
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  2. Andres Rubiano
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  3. Daniel Stewart
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  4. Brandey Andersen
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Corresponding author

Correspondence to Chelsey Simmons .

Editor information

Editors and Affiliations

  1. Department of Mechanical Engineering, State University of New York at Stony Brook, Stony Brook, New York, USA

    Chad S. Korach

  2. Michigan State University , East Lansing, Michigan, USA

    Srinivasan Arjun Tekalur

  3. Purdue University, West Lafayette, Indiana, USA

    Pablo Zavattieri

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© 2017 The Society for Experimental Mechanics, Inc.

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Simmons, C., Rubiano, A., Stewart, D., Andersen, B. (2017). Custom Indentation System for Mechanical Characterization of Soft Matter. In: Korach, C., Tekalur, S., Zavattieri, P. (eds) Mechanics of Biological Systems and Materials, Volume 6. Conference Proceedings of the Society for Experimental Mechanics Series. Springer, Cham. https://doi.org/10.1007/978-3-319-41351-8_14

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  • DOI: https://doi.org/10.1007/978-3-319-41351-8_14

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-41350-1

  • Online ISBN: 978-3-319-41351-8

  • eBook Packages: EngineeringEngineering (R0)

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