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Acne Vulgaris

  • Marina de Almeida Delatti
  • Renan Lage
  • Elisa Moraes
  • Beatrice Abdalla
  • Marcel dos Santos
  • Adilson Costa
Chapter

Abstract

Acne vulgaris is a common and chronic inflammatory disease with a complex pathophysiology, including increased sebum production, follicular hyperkeratinization, bacterial colonization, inflammation, as well as hormonal involvement and genetic association with diet and smoking. The clinical picture consists of inflammatory and noninflammatory lesions mainly on the face and upper trunk that may progress to scarring. Topical and/or systemic treatment should be initiated early with a prolonged course, and also requires good patient compliance.

Keywords

Acne Pilosebaceous follicle Propionibacterium acnes Hyperkeratinization Comedones Papules Pustules Nodules Cysts Hyperandrogenism Isotretinoin Retinoids Azelaic acid Antibiotics Elaioconiosis Chloracne Benzoyl peroxide 

Notes

Glossary

Comedo

A hair follicle infundibulum that is dilated and plugged by keratin and lipids. The lesion is referred to as an open comedo when the pilosebaceous unit is open to the surface of the skin with a visible keratinaceous plug. A closed comedo occurs when the follicular opening is unapparent and accumulates whitish keratin.

Cyst

An encapsulated cavity or sac lined with a true epithelium that contains fluid or semisolid material (cells and cell products such as keratin).

Nodule

A solid round or ellipsoidal, palpable lesion of diameter larger than 0.5 cm. Depth of involvement and/or substantive palpability, rather than diameter, differentiates a nodule from a large papule or plaque. Nodules are of five main types: epidermal, epidermal-dermal, dermal, dermal-subdermal, and subcutaneous.

Papule

A solid, elevated lesion less than 0.5 cm in size in which a significant portion projects above the plane of the surrounding skin.

Pustule

A circumscribed, raised cavity in the epidermis or infundibulum containing pus; may contain bacteria or be sterile. Pustules may vary in size and, in certain situations, may coalesce to form lakes of pus.

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Copyright information

© Springer International Publishing Switzerland 2018

Authors and Affiliations

  • Marina de Almeida Delatti
    • 1
  • Renan Lage
    • 2
  • Elisa Moraes
    • 1
  • Beatrice Abdalla
    • 3
  • Marcel dos Santos
    • 1
  • Adilson Costa
    • 4
  1. 1.Service of Dermatology of the Pontifical CatholicUniversity of Campinas (PUC-Campinas)CampinasBrazil
  2. 2.Hospital e Maternidade Celso Pierro – PUC CampinasCampinasBrazil
  3. 3.ABC School of MedicineSanto AndreBrazil
  4. 4.State Public Workers Welfare InstituteSão PauloBrazil

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