Basal Cell Carcinoma
Basal cell carcinoma (BCC) is the most incident type of skin cancer, having been related etiologically to chronic sun exposure and genetic predisposition. The classical clinical presentation of BCC is a slow-growing pearly papule, showing telangiectatic vessels that can progress to nodules. Different clinical and histologic subtypes are described, whose recognition is of great importance in arriving at the correct therapeutic decision and oncologic cure.
KeywordsBasal cell carcinoma Skin cancer Nonmelanoma skin cancer
Noninvasive imaging technique that enables in vivo visualization of the skin structure in real time.
Noninvasive diagnostic technique for the in vivo observation of skin lesions with a dermatoscope, allowing magnification of the lesion.
Also known as nevoid basal cell carcinoma syndrome, it is characterized by developmental anomalies, such as odontogenic keratocysts of the mandible, bifid ribs, palmoplantar pits and tumors, and especially multiple BCCs.
A microscopically controlled surgery used to treat different types of skin cancer, developed in 1938 by Frederic Mohs.
Noninvasive imaging examination that uses light waves to take cross-sectional pictures of the skin structure.
Treatment that uses a photosensitizer or photosensitizing agent that will be absorbed by the target cell, and a particular type of light that will react with the photosensitizer and cause cellular death.
This gene encodes the protein receptor for the sonic hedgehog, a molecule implicated in the formation of embryonic structures and in tumorigenesis. Mutations of this gene have been associated with basal cell nevus syndrome and sporadic BCC.
Dilated capillaries that appear clinically as red linear vessels with spidery appearance on the surface of the skin.
- 3.Cancer INd. Câncer de Pele Não Melanoma http://www2.inca.gov.br/wps/wcm/connect/tiposdecancer/site/home/pele_nao_melanoma2016. (Cited 2016 30 Apr).
- 9.Colins S. Basal cell carcinoma. Clinical presentation. In: Miller SJ MM, editor. Cutaneous oncology. Malden, MA: 1: Wiley-Blackwell; 1998. pp. 625–32.Google Scholar
- 18.Arits AH, Mosterd K, Essers BA, Spoorenberg E, Sommer A, De Rooij MJ, et al. Photodynamic therapy versus topical imiquimod versus topical fluorouracil for treatment of superficial basal-cell carcinoma: a single blind, non-inferiority, randomised controlled trial. Lancet Oncol. 2013;14(7):647–54.CrossRefPubMedGoogle Scholar