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Critical Illness-Related Corticosteroid Insufficiency in the Intensive Care Patient

  • Noelle N. Saillant
  • Carrie Sims
Chapter

Abstract

Managing critical illness-related corticosteroid insufficiency (CIRCI) is a challenging endeavor for the surgical intensivist. The mechanisms underlying CIRCI remain incompletely characterized. Moreover, optimal methods of diagnosing and managing CIRCI remain to be determined. This chapter will summarize the salient features of CIRCI and review the best available guidelines for treating this complex disorder.

Keywords

Critical illness-related corticosteroid insufficiency (CIRCI) Stress dose steroids Glucocorticoids Hypothalamic-pituitary (HPA) axis Adrenal insufficiency 

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© Springer International Publishing Switzerland 2016

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Authors and Affiliations

  1. 1.Department of Surgery, Beth Israel Deaconess Medical CenterBostonUSA
  2. 2.Division of Trauma, Surgical Critical Care, and Emergency Surgery, Department of SurgeryUniversity of PennsylvaniaPhiladelphiaUSA

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