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Coagulopathies and Anticoagulation

  • Jeremy W. Cannon
Chapter

Abstract

Acute hemorrhage, acute thrombosis, and management of anticoagulation are common challenges in critical care medicine. An array of acquired conditions result in coagulopathy. These include liver disease, acute trauma, cardiopulmonary bypass, and anticoagulation with both standard and novel agents. Furthermore, congenital or acquired conditions such as von Willebrand disease and hemophilia can complicate otherwise straightforward surgery or can result in life-threatening bleeding from relatively minor trauma. Patients also frequently require the initiation or discontinuation of anticoagulation while in the ICU. The following chapter describes the most common coagulopathies seen in the ICU and outlines a practical management approach to reversing coagulopathy and managing anticoagulation in the critical care setting.

Keywords

Coagulopathy Hemorrhage Hemostasis Thrombosis Anticoagulation 

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Authors and Affiliations

  1. 1.Division of Traumatology, Surgical Critical Care & Emergency SurgeryPenn Presbyterian Medical CenterPhiladelphiaUSA

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