Application of Visible and Solar Light in Organic Synthesis

  • Davide Ravelli
  • Stefano Protti
  • Maurizio FagnoniEmail author
Part of the Lecture Notes in Chemistry book series (LNC, volume 92)


This chapter highlights the impressive recent developments (mainly focused in the 2013–2015 period) in the use of visible and solar light to promote valuable organic transformations, virtually inaccessible under thermal conditions. Compact fluorescent lamps (CFL), LEDs and even ambient sunlight were used as the light sources. The photochemical approach was applied, among others, to ring formation, arylations, additions onto C=C bond, alpha- and beta- functionalization of carbonyls, (de)halogenations, oxidations and reductions. The last part comprises some exemplary cases of the synthesis of bioactive compounds.


Photocatalytic Reduction Graphitic Carbon Nitride Compact Fluorescent Lamp Aryldiazonium Salt Hypervalent Iodine 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. 1.
    Fagnoni M, Albini A (2008) The greenest reagent in organic synthesis: light. In: Tundo P, Esposito V (eds) Green chemical reactions. NATO science for peace and security series. Springer, Dordrect/London, pp 173–189Google Scholar
  2. 2.
    Hoffmann N (2012) Photochemical reactions of aromatic compounds and the concept of the photon as a traceless reagent. Photochem Photobiol Sci 11:1613–1643CrossRefGoogle Scholar
  3. 3.
    Albini A, Fagnoni M (2013) Photochemically-generated intermediates in synthesis. Wiley, HobokenCrossRefGoogle Scholar
  4. 4.
    Ravelli D, Protti S, Albini A (2015) Energy and molecules from photochemical/photocatalytic reactions. An overview. Molecules 20:1527–1542CrossRefGoogle Scholar
  5. 5.
  6. 6.
    Schultz DM, Yoon TP (2014) Solar synthesis: prospects in visible light photocatalysis. Science 343:1239176-1-1239176–8CrossRefGoogle Scholar
  7. 7.
    Kalogirou SA (2004) See for reviews: solar thermal collectors and applications. Prog Energy Combust 30:231–295CrossRefGoogle Scholar
  8. 8.
    Tian Y, Zhao CY (2013) A review of solar collectors and thermal energy storage in solar thermal applications. Appl Energy 104:538–553CrossRefGoogle Scholar
  9. 9.
    Lennartson A, Roffey A, Moth-Poulsen K (2015) Designing photoswitches for molecular solar thermal energy storage. Tetrahedron Lett 56:1457–1465CrossRefGoogle Scholar
  10. 10.
    Parida B, Iniyan S, Goic R (2011) A review of solar photovoltaic technologies. Renew Sustain Energy Rev 15:1625–1636CrossRefGoogle Scholar
  11. 11.
    Razykov TM, Ferekides CS, Morel D, Stefanakos E, Ullal HS, Upadhyay HM (2011) Solar photovoltaic electricity: current status and future prospects. Sol Energy 85:1580–1608CrossRefGoogle Scholar
  12. 12.
    El Chaar L, Lamont LA, El Zein N (2011) Review of photovoltaic technologies. Renew Sustain Energy Rev 15:2165–2175CrossRefGoogle Scholar
  13. 13.
    Bard AJ, Fox MA (1995) Artificial photosynthesis: solar splitting of water to hydrogen and oxygen. Acc Chem Res 28:141–145CrossRefGoogle Scholar
  14. 14.
    Walter MG, Warren EL, McKone JR, Boettcher SW, Mi Q, Santori EA, Lewis NS (2010) Solar water splitting cells. Chem Rev 110:6446–6473CrossRefGoogle Scholar
  15. 15.
    Kudo A, Miseki Y (2009) Heterogeneous photocatalyst materials for water splitting. Chem Soc Rev 38:253–278CrossRefGoogle Scholar
  16. 16.
    Bradbury R (1953) The golden apples of the sun. Doubleday & Company, Inc, Garden City, New YorkGoogle Scholar
  17. 17.
    Ciamician G (1912) Photochemistry of the future. Science 36:385CrossRefGoogle Scholar
  18. 18.
    Albini A, Dichiarante V (2009) The belle époque of photochemistry. Photochem Photobiol Sci 11:248–254CrossRefGoogle Scholar
  19. 19.
    Fagnoni M, Albini A (2004) Green chemistry and photochemistry were born at the same time. Green Chem 6:1–6CrossRefGoogle Scholar
  20. 20.
    Schenck GO, Ziegler K (1945) The synthesis of ascaridole. Naturwissenschaften 32:157Google Scholar
  21. 21.
    Esser P, Pohlmann B, Scharf H-D (1994) The photochemical synthesis of fine chemicals with sunlight. Angew Chem Int Ed 33:2009–2023CrossRefGoogle Scholar
  22. 22.
    Oelgemöller M, Jung C, Mattay J (2007) Green Photochemistry: production of fine chemicals with sunlight. Pure Appl Chem 79:1939–1947CrossRefGoogle Scholar
  23. 23.
    For a review of the advancements in the field of solar photochemistry until 2010 see: Protti S, Fagnoni M (2009) The sunny side of chemistry: green synthesis by solar light. Photochem Photobiol Sci 8:1499–1516Google Scholar
  24. 24.
    Mumtaz S, Sattler C, Oelgemöller M (2015) Solar photochemical manufacturing of fine chemicals: historical background, modern solar technologies, recent applications and future challenges. In: Letcher TM, Scott JL, Patterson DA (eds) Chemical processes for a sustainable future. The Royal Society of Chemistry, CambridgeGoogle Scholar
  25. 25.
    Spasiano D, Marotta R, Malato S, Fernandez-Ibaňez P, Di Somma I (2015) Solar photocatalysis: materials, reactors, some commercial, and pre-industrialized applications. A comprehensive approach. Appl Catal B-Environ 170:90–123CrossRefGoogle Scholar
  26. 26.
    Maidan R, Goren Z, Becker JY, Willner I (1984) Application of multielectron charge relays in chemical and photochemical debromination processes. The role of induced disproportionation of N, N′-dioctyl-4,4′-bipyridinium radical cation in two-phase systems. J Am Chem Soc 106:6217–6222CrossRefGoogle Scholar
  27. 27.
    Cano-Yelo H, Deronzier A (1984) Photocatalysis of the Pschorr reaction by tris-(2,2′-bipyridyl)ruthenium(II) in the phenanthrene series. J Chem Soc Perkin Trans 2:1093–1098CrossRefGoogle Scholar
  28. 28.
    Ravelli D, Protti S, Fagnoni M, Albini A (2013) Visible light photocatalysis. A green choice? Curr Org Chem 17:2366–2373CrossRefGoogle Scholar
  29. 29.
    Schultz DM, Yoon TP (2014) Solar synthesis: prospects in visible light photocatalysis. Science 343:1239176CrossRefGoogle Scholar
  30. 30.
    Knowles JP, Elliott LD, Booker-Milburn KI (2012) Flow photochemistry: old light through new windows. Beilstein J Org Chem 8:2025–2052CrossRefGoogle Scholar
  31. 31.
    Oelgemöller M (2012) Highlights of photochemical reactions in microflow reactors. Chem Eng Technol 35:1144–1152CrossRefGoogle Scholar

Copyright information

© Springer International Publishing Switzerland 2016

Authors and Affiliations

  • Davide Ravelli
    • 1
  • Stefano Protti
    • 1
  • Maurizio Fagnoni
    • 1
    Email author
  1. 1.PhotoGreen Lab, Department of ChemistryUniversity of PaviaPaviaItaly

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