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A Matching Model Based on Earth Mover’s Distance for Tracking Myxococcus Xanthus

  • Jianxu Chen
  • Cameron W. Harvey
  • Mark S. Alber
  • Danny Z. Chen
Part of the Lecture Notes in Computer Science book series (LNCS, volume 8674)

Abstract

Tracking the motion of Myxococcus xanthus is a crucial step for fundamental bacteria studies. Large number of bacterial cells involved, limited image resolution, and various cell behaviors (e.g., division) make tracking a highly challenging problem. A common strategy is to segment the cells first and associate detected cells into moving trajectories. However, known detection association algorithms that run in polynomial time are either ineffective to deal with particular cell behaviors or sensitive to segmentation errors. In this paper, we propose a polynomial time hierarchical approach for associating segmented cells, using a new Earth Mover’s Distance (EMD) based matching model. Our method is able to track cell motion when cells may divide, leave/enter the image window, and the segmentation results may incur false alarm, detection lost, and falsely merged/split detections. We demonstrate it on tracking M. xanthus. Applied to error-prone segmented cells, our algorithm exhibits higher track purity and produces more complete trajectories, comparing to several state-of-the-art detection association algorithms.

Keywords

Match Model Cell Tracking Segmentation Error Image Boundary Image Window 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer International Publishing Switzerland 2014

Authors and Affiliations

  • Jianxu Chen
    • 1
  • Cameron W. Harvey
    • 2
  • Mark S. Alber
    • 2
    • 1
  • Danny Z. Chen
    • 1
  1. 1.Department of Computer Science and EngineeringUniversity of Notre DameUSA
  2. 2.Department of Appl. and Comput. Math and Stat.University of Notre DameUSA

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