In this paper we propose a new method for shape analysis based on the depth-ordering of shapes. We use this depth-ordering to non-parametrically define depth with respect to a normal control population. This allows us to quantify differences with respect to “normality”. We combine this approach with a permutation test allowing it to test for localized shape differences. The method is evaluated on a synthetically generated striatum dataset as well as on a real caudate dataset.


Personality Disorder Shape Analysis Test Shape Band Depth Schizotypal Personality Disorder 
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Copyright information

© Springer International Publishing Switzerland 2014

Authors and Affiliations

  • Yi Hong
    • 1
  • Yi Gao
    • 3
  • Marc Niethammer
    • 1
    • 2
  • Sylvain Bouix
    • 4
  1. 1.University of North Carolina (UNC) at Chapel HillUSA
  2. 2.Biomedical Research Imaging CenterUNC-Chapel HillUSA
  3. 3.University of Alabama at BirminghamBirminghamUSA
  4. 4.Psychiatry Neuroimaging Laboratory, Brigham and Women’s HospitalHarvard Medical SchoolBostonUSA

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