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fhSPECT-US Guided Needle Biopsy of Sentinel Lymph Nodes in the Axilla: Is it Feasible?

  • Aslı Okur
  • Christoph Hennersperger
  • Brent Runyan
  • José Gardiazabal
  • Matthias Keicher
  • Stefan Paepke
  • Thomas Wendler
  • Nassir Navab
Part of the Lecture Notes in Computer Science book series (LNCS, volume 8673)

Abstract

Until now, core needle biopsy of the axillary sentinel lymph nodes in early stage breast cancer patients is not possible, due to the lack of a proper combination of functional and anatomical information. In this work we present the first fully 3D freehand SPECT - ultrasound fusion, combining the advantages of both modalities. By using spatial positioning either with optical or with electromagnetic tracking for the ultrasound probe, and a mini gamma camera as radiation detector for freehand SPECT reconstructions, we investigate the capability of the introduced multi-model imaging system, where we compare both 3D freehand SPECT and 3D ultrasound to ground truth for a realistic breast mimicking phantom and further analyze the effect of tissue deformation by ultrasound. Finally, we also show its application in a real clinical setting.

Keywords

Sentinel Lymph Node Sentinel Lymph Node Biopsy Core Needle Biopsy Optical Tracking Reference Target 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer International Publishing Switzerland 2014

Authors and Affiliations

  • Aslı Okur
    • 1
    • 2
    • 3
  • Christoph Hennersperger
    • 1
  • Brent Runyan
    • 1
  • José Gardiazabal
    • 1
    • 2
  • Matthias Keicher
    • 4
  • Stefan Paepke
    • 3
  • Thomas Wendler
    • 4
  • Nassir Navab
    • 1
    • 5
  1. 1.Computer Aided Medical ProceduresTechnische Universität MünchenGermany
  2. 2.Department of Nuclear MedicineTechnische Universität MünchenGermany
  3. 3.Department of GynecologyTechnische Universität MünchenGermany
  4. 4.SurgicEye GmbHMunichGermany
  5. 5.Computer Aided Medical ProceduresJohns Hopkins UniversityUSA

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